Results 71 to 80 of about 759 (134)
Dengue is an arbovirus that has become a serious public health problem in Brazil, as well as in other tropical regions of the world due to population, economic, political, and social factors that contribute to the proliferation, circulation, and ...
Damião Sampaio de Sousa +5 more
doaj +1 more source
Isoflavones and Rotenoids from the Leaves of Millettia oblata ssp. teitensis
A new isoflavone, 8-prenylmilldrone (1), and four new rotenoids, oblarotenoids A−D (2−5), along with nine known compounds (6−14), were isolated from the CH2Cl2/CH3OH (1:1) extract of the leaves of Millettia oblata ssp.
Deyou, Tsegaye, +38 more
core +1 more source
Antiplasmodial and larvicidal flavonoids from Derris trifoliate
From the dichloromethane-methanol (1:1) extract of the seed pods of Derris trifoliata, a new flavanone derivative (S)-lupinifolin 4´-methyl ether was isolated. In addition, the known flavonoids lupinifolin and rotenone were identified.
Abiy Yenesew +9 more
doaj
Anti-Angiogenic Activity of Rotenoids from the Stems of Derris trifoliata
The plants in the genus Derris have proven to be a rich source of rotenoids, of which cytotoxic effect against cancer cells seem to be pronounced. However, their effect on angiogenesis playing a crucial role in both cancer growth and metastasis has been ...
Khanitha Pudhom +4 more
core +1 more source
Nonprenylated rotenoids, a new class of potent breast cancer resistance protein inhibitors.
International audienceTwo rotenoids isolated from Boerhaavia diffusa (Nyctaginaceae), boeravinones G (1) and H (2), have been found to potently inhibit the drug efflux activity of breast cancer resistance protein (BCRP/ABCG2), a multidrug transporter ...
Fattorusso, E. +6 more
core +4 more sources
The control of parasitic roundworms (nematodes) is heavily reliant on the use of a limited number of anthelmintic drugs. However, drug resistance is now very widespread and no vaccines are available, such that the discovery of new chemical entities is ...
Davis, RA +7 more
core +2 more sources
An Intramolecular CAr–H•••O=C Hydrogen Bond and the Configuration of Rotenoids
Over the past half a century, the structure and configuration of the rotenoids, a group of natural products showing multiple promising bioactivities, have been established by interpretation of their NMR and electronic circular dichroism spectra and ...
A. Kinghorn, Judith Gallucci, Yulin Ren
core +1 more source
Flavanones and rotenoids from the roots of Amorpha fruticosa L. that inhibit bacterial neuraminidase
Neuraminidase is a proven target in anti-viral drug development. It also appears to be important for infection by certain pathogenic bacteria and has been implicated in biofilm formation.
M J Curtis-Long +8 more
core +1 more source
Nonprenylated Rotenoids, a New Class of Potent Breast Cancer Resistance Protein Inhibitors
Two rotenoids isolated from Boerhaavia diffusa (Nyctaginaceae), boeravinones G (1) and H (2), have been found to potently inhibit the drug efflux activity of breast cancer resistance protein (BCRP/ABCG2), a multidrug transporter responsible for cancer ...
Sira Macalou (2495500) +6 more
core +1 more source
Millettia isoflavonoids: a comprehensive review of structural diversity, extraction, isolation, and pharmacological properties. [PDF]
Desta KT, Abd El-Aty AM.
europepmc +1 more source

