Results 191 to 200 of about 65,398 (283)

Wild‐Derived House Mice (Mus musculus) Are Able to Cope With a Constant Light Environment

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 345, Issue 2, Page 162-171, March 2026.
ABSTRACT Exposure to altered nighttime lighting conditions has become common in today's modern world. Light at night disrupts circadian processes that govern feeding patterns, sleep/wake cycles, and metabolic homoeostasis, increasing the risk of developing pathologies associated with cardiometabolic disease. Yet, the underlying mechanism(s) responsible
Kevin Pham, KayLene Y. H. Yamada, Emma M. Rhodes, Agata. M. Rudolf, Wendy R. Hood   +4 more
wiley   +1 more source

Red and near-infrared light treatment can change the intensity of biophoton emissions in cell culture. [PDF]

Sci Rep
Hoh Kam J, Clément R, Cantat-Moltrecht T, Billères M, Mitrofanis J.   +4 more
europepmc   +1 more source

Mild Short‐Term Caloric Restriction Induces Coordinated Changes That Promote Lipid Deposition While Maintaining Thermogenesis Capacity in Interscapular Brown Adipose Tissue of Male Rats

The FASEB Journal, Volume 40, Issue 3, 15 February 2026.
Rats under mild caloric restriction (85% vs. ad libitum) for 2 weeks show metabolic and structural adaptations in iBAT. Caloric restriction increases glycolysis and triglyceride deposition in the tissue, leading to larger lipid droplets. It also reduces mitochondrial iBAT content, while maintaining iBAT thermogenic potential thanks to an increased ...
Giuliana Panico, Vincenzo Migliaccio, Gabriella Pinto, Anna Iliano, Gianluca Fasciolo, Martina Coletta, Paola Venditti, Maria Moreno, Angela Amoresano, Pieter de Lange, Lillà Lionetti, Assunta Lombardi   +11 more
wiley   +1 more source

Rotenone accelerates endogenous α-synuclein spreading and enhances neurodegeneration in an intra-striatal α-synuclein preformed fibril injected mouse model of Parkinson's disease. [PDF]

Front Cell Neurosci
Khan E, Radwan N, Ardah MT, Kitada T, Haque ME.   +4 more
europepmc   +1 more source

Design, Synthesis, and Biological Evaluation of Pseudo‐Natural Products Inspired by Aryloctahydroindole Alkaloids

ChemMedChem, Volume 21, Issue 3, 12 February 2026.
Mesembrine alkaloid pseudo‐natural products were synthesized employing a microwave‐assisted Diels–Alder reaction as a key step. Morphological profiling by cell painting revealed compound‐topology‐dependent mitochondrial fragmentation or inhibition of respiration.
Luca C. Greiner, Freddy A. Bernal, Sasikala Thavam, Maite Brachthäuser, Sonja Sievers, Slava Ziegler, Herbert Waldmann   +6 more
wiley   +1 more source

p75NTR Modulation by LM11A-31 Counteracts Oxidative Stress and Cholesterol Dysmetabolism in a Rotenone-Induced Cell Model of Parkinson's Disease. [PDF]

Neurochem Res
Pensabene D, Martella N, Scavo G, Bisesto E, Cavicchia F, Colardo M, Varone M, Moreno S, Segatto M.   +8 more
europepmc   +1 more source

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

Advanced Science, Volume 13, Issue 8, 9 February 2026.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu, Jing Luo, Li Yu, Daoxi Qi, Boyu Li, Yating Chen, Chen Wang, Xiaokang Zhang, Wenzheng Guo, Qiyong Lou, Gang Zhai, Yonglin Ruan, Jianfei Huang, Shengchi Shi, Zhan Yin, Fang Zheng   +15 more
wiley   +1 more source

Inhibition of pro-apoptotic UPR pathways PERK/CHOP and IRE1/JNK protects differentiated SH-SY5Y cells against rotenone-induced toxicity. [PDF]

Front Mol Neurosci
Siwecka N, Rozpȩdek-Kamińska W, Golberg M, Wiese W, Galita G, Majsterek I.   +5 more
europepmc   +1 more source

Single‐Cell Metabolic Imaging Reveals Glycogen‐Driven Adaptations in Endothelial Cells

Advanced Science, Volume 13, Issue 7, 3 February 2026.
Single‐cell metabolic imaging of diabetes‐associated endothelial dysfunction by SRS microscopy reveals dynamic glycogen storage and its role in modulating metabolic adaptations under glucose starvation. Abstract Endothelial dysfunction (ED) is a defining feature of diabetes mellitus (DM) and a key contributor to many metabolic and cardiovascular ...
Rahuljeet S. Chadha, Benjamin Yang, Dongqiang Yuan, Edmund D. Kapelczak, Philip A. Kocheril, Alonso Tapia, Shivansh Mahajan, Adrian Colazo, Naseeb K. Malhi, Joseph A. Ambarian, Xuejing Liu, Tara A. TeSlaa, Zhen B. Chen, Lu Wei   +13 more
wiley   +1 more source

ZC3H4, a novel regulator of mitochondrial complex I, impacts prostate stromal cell senescence, attachment, adhesion and anoikis resistance. [PDF]

Cell Death Dis
Liu TT, Carrarini MJ, Myklebust LK, Skalitzky KO, El-Khoury N, Sipula IJ, Chang A, Soman V, Liu A, Ihejirika N, Chandran UR, Jurczak MJ, Ricke WA, DeFranco DB, Pascal LE.   +14 more
europepmc   +1 more source