Results 171 to 180 of about 38,087 (260)

Mitochondrial Carrier SLC25A13 Drives Ferroptosis Resistance and Immune Evasion via a STAT3–IFI6 Circuit in Breast Cancer

Advanced Science, Volume 13, Issue 46, 17 August 2026.
SLC25A13 is identified as an immunometabolic driver of triple‐negative breast cancer that sustains ferroptosis resistance and immune evasion through a STAT3–IFI6 circuit. Pharmacologic degradation of SLC25A13 restores ferroptosis sensitivity and enhances anti‐PD‐1 efficacy, highlighting a strategy to convert immune‐cold tumors into immunotherapy ...
Yingze Zhu, Yuhan Tang, Yingcui Chen, Zhuoqi Zhang, Yige Lu, Xinyue Wang, Qiyuan Shi, Wenhui Zhao, Hui Pang   +8 more
wiley   +1 more source

Optical and Microdialysis Monitoring of Succinate Prodrug Treatment in a Rotenone-Induced Model of Mitochondrial Dysfunction in Swine. [PDF]

Metabolites
Lewis A, Forti RM, Ko TS, Elmér E, McManus MJ, Yodh AG, Kilbaugh TJ, Baker WB.   +7 more
europepmc   +1 more source

A Plasmonic Biohybrid With an Intracellular Biogenic S‐Scheme Nano‐Heterojunction Toward Wide‐Spectrum Solar‐To‐Chemical Conversion Beyond Nature

Aggregate, Volume 7, Issue 8, August 2026.
Bioinorganic hybrids show promise for solar‐to‐chemical conversion, yet are limited by poor light absorption and charge separation. A plasmonic biohybrid (CuS/CdS@yeast), featuring an intracellular S‐scheme heterojunction to achieve efficient electron‐hole separation, is fabricated via in‐situ mineralization for wide‐spectrum solar‐to‐chemical ...
Heng Yu, Tingting Guo, Guanglei Ma, Xueqing Ren, Yue Zhang, Ruijuan Qi, Nana Ma, Meilin Wei, Yi Chang, Xiaoming Ma   +9 more
wiley   +1 more source

Protocol for automated quantification of neuronal cells using the Agilent BioTek Cytation system and Gen5 neurite outgrowth module. [PDF]

STAR Protoc
Broeglin A, Buetzberger O, Mongeon R, Riou A, Eckert A, Grimm A.   +5 more
europepmc   +1 more source

Epigenetic Mechanisms Underlying Cognitive Dysfunction in Parkinson's Disease: Current Evidence and Future Prospects

Brain and Behavior, Volume 16, Issue 8, August 2026.
Epigenetic mechanismsincluding DNA methylation, histone modifications, and microRNA (miRNA) regulationmodulate gene expression without altering the DNA sequence and are increasingly implicated in the cognitive impairment associated with Parkinson's disease (PD). Environmental and molecular factors influence these epigenetic pathways, leading to altered
Fatemeh Hasani, Mohammad Ebrahim Kherad, Mohammad Sharifi Sarasyabi, Kimia Jazi, Ali Ashkbari, Payam Ahmadi, Hadise Heidarpour, Mahdi Masrour, Sina Khamaki, Rahem Rahmati, Andrei Surguchov   +10 more
wiley   +1 more source

Emphasizing the role of oxidative stress and Sirt-1/Nrf2 and TLR-4/NF-κB in Tamarix aphylla mediated neuroprotective potential in rotenone-induced Parkinson's disease: In silico and in vivo study. [PDF]

PLoS One
Abu-Baih DH, Elmaidomy AH, Abou-Zied HA, Hussien NA, Rasekh MI, Saber EA, Ali SFE, Rateb ME, Hendawy OM, Altemani FH, Altemani AH, Bringmann G, Abdelmohsen UR, Abdelhafez OH.   +13 more
europepmc   +1 more source

The Neuroprotective Potentials of Dual GIP/GLP1‐RA (Tirzepatide): From Preclinical Experiments to Clinical Trials: A Scoping Review

Brain and Behavior, Volume 16, Issue 8, August 2026.
The graphical abstract summarizes the current evidence on the potential neuroprotective effects of tirzepatide (TZP), a dual GIP/GLP‐1 receptor agonist, across mechanistic, preclinical, and clinical domains. Mechanistically, TZP is proposed to exert direct neural effects, preserve mitochondrial function, reduce apoptosis, oxidative stress, and ...
Yousef Hawas, Mohamed Abouzid, Ahmed Farid Gadelmawla, Dalia Kamal Ewis, Abdallah Khatatbeh, Yasmin Negida, Ahmed Negida   +6 more
wiley   +1 more source

Enteric Nervous System Damage by Food Contaminants: A Pathway to Neurodegeneration? [PDF]

Compr Rev Food Sci Food Saf
Ramos H, Araújo AM, Ferreira IMPLVO, Faria MA.   +3 more
europepmc   +1 more source

A Novel Nogo‐A Receptor Antagonist Peptide Impedes Alzheimer's Disease Pathology by Nogo‐A/NgR/ROCK Signaling Pathway

CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
NAP2, a NgR1 antagonist peptide, improved cognition in APP/PS1 mice, reduced Aβ plaques and tau hyperphosphorylation, increased dendritic spine density, and alleviated mitochondrial damage, acting through inhibition of the Nogo‐A/NgR/ROCK pathway, highlighting its therapeutic potential for Alzheimer's disease.
Zheng Zhang, Huimin Tan, Fang Shi, Jiajia Dai, Weilong Ding, Junliang Li, Yuke Wang, Rui Yang, Xinke Xu, Cheng Chen, Fei Xiao, Li‐an Huang, Xiaoyan Liu, Rui Liao, Li Yan   +14 more
wiley   +1 more source

Prebiotics attenuate depressive-like behavior, neuroinflammation and synaptic plasticity in Parkinson's disease by modulating butyrate-producing gut bacteria. [PDF]

Inflammopharmacology
de Mendonça IP, da Silva RS, de Paiva IHR, da S A Costa BL, de Sousa Barbosa Teixeira KP, de Souza JRB, Peixoto CA.   +6 more
europepmc   +1 more source