Results 81 to 90 of about 43,287 (200)

Neuroprotection in a rotenone model of Parkinson's disease [PDF]

, 2015
The pesticide/neurotoxin, rotenone, has been shown to cause systemic inhibition of mitochondrial complex I activity, with consequent degeneration of the nigrostriatal pathway, as observed in Parkinson’s disease.
Carriere, Candace
core  

Evaluation of the Neuroprotective Potential of Sutherlandia frutescens in a Rotenone-Induced Rat Model of Parkinson’s Disease

Behavioural Neurology
Sutherlandia frutescens (SF) is a plant used traditionally in South Africa for various health conditions, including neurological disorders. Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by the degeneration of ...
Lilit Darbinyan, Karen Simonyan, Larisa Manukyan, Vaghinak Sarkisian, Lusya Hovhannisyan, Lilia Hambardzumyan   +5 more
doaj   +1 more source

Rotenone induced inflammasome activation in BV2 cells.

, 2013
(A) BV2 cells were treated with 1 µM rotenone or 1 µg/mL LPS for 24 hours and then stained with green fluorescent probes for activated caspase-1 for 1 hour. The scale bar represents 10 µm.
Feng Gao (3548), Qingsong Hu (448285), Dong Chen (448284), Guanghui Wang (51854)   +3 more
core   +1 more source

Common Pesticide Rotenone Interference with Neuronal Transmission in Hippocampus

, 2020
Rotenone is a pesticide and piscicide, wh ich causes behavioral and biochemical changes in rats that closely resemble PD sympto ms in hu mans. Rotenone is a naturally occurring ret inoid plant ext ract derived fro m the roots of certain tropical and ...
Yusuf P Tan, Hale Saybasili, Fatih Akkentli   +2 more
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Idebenone protects against rotenone-induced gliosis.

, 2012
For analysis of gliosis 7 days after intravitreal injection of rotenone or DMSO (Sham), mice were treated with dietary idebenone (IDE 200, 400 and 2000 mg/kg body weight) or vehicle. (A) Images of retinal slices stained with anti-GFAP primary antibody to
Corinne Anklin (134641), Dimitri Robay (134646), Michael Erb (134635), Nuri Gueven (134653), Fabrice D. Heitz (134630), Vincent Pernet (134650)   +5 more
core   +1 more source

Normal soaking extraction (NSE) of rotenone from Derris elliptica [PDF]

, 2004
Derris elliptica or the tuba plant contains rotenone, bio-active compound known that has the potential to be used as bio-pesticide. Bio-pesticide is the best-known alternative bio-pesticide which has the potential to replace the use of conventional ...
Nordin, N. I. A., Zubairi, Saiful Irwan, Latip, R., Ramli, M. K. A., Aziz, R. A., Sarmidi, M. R.   +5 more
core  

Network Toxicology and Transcriptomic Analyses Reveal Ferroptosis-Related Neurotoxicity of Rotenone as an Environmental Hazardous Compound. [PDF]

Cells
Chen Y, Zhang D, Ma J, Li H, Xu J, Ma C, Liu Y, Zhao Z, Duffy GP, Ma J, Cui H.   +10 more
europepmc   +1 more source

The first enantioselective synthesis of the natural pesticide, rotenone

, 2012
MSc., Faculty of Science, University of the Witwatersrand, 2011The 2-isopropenyl-2,3-dihydrobenzofuran moiety is found in many naturally occurring compounds including rotenone, a complex pentacyclic molecule isolated from several leguminous plants of the
Georgiou, Kathy Hadje
core  

Rotenone Inhibited Osteosarcoma Cell Growth Through USP47-Induced Decreases in FEN1 Stability and DNA Integrity. [PDF]

Drug Des Devel Ther
Li Z, Ma X, Ma H, Chen B, Jiang K, Zhu Z, Wang J, Wang B, Wang Y, Dong S.   +9 more
europepmc   +1 more source

Behavioral Effects of Renin-Angiotensin System Modulators in a Rotenone-Induced Model of Parkinson's Disease in Wistar Albino Rats. [PDF]

Cureus
Kg P, K S, Mantri A, Chavan M, K MB, Jaju S.   +5 more
europepmc   +1 more source