Results 51 to 60 of about 3,667,485 (307)

Role of atrial tissue remodeling on rotor dynamics: an in vitro study.

American Journal of Physiology. Heart and Circulatory Physiology, 2015
The objective of this article is to present an in vitro model of atrial cardiac tissue that could serve to study the mechanisms of remodeling related to atrial fibrillation (AF).
A. Climent, M. Guillem, Lucia Fuentes, Peter Lee, C. Bollensdorff, M. Fernández-Santos, S. Suárez-Sancho, R. Sanz-Ruiz, P. Sánchez, F. Atienza, F. Fernández‐Avilés   +10 more
semanticscholar   +1 more source

Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy

Advanced Materials, EarlyView.
Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla, Jacqueline J. Li, Qunzhou Zhang, Korey Patwari, Shihong Shi, Hannah M. Yamagata, Ryann A. Joseph, Briyanna N. Hymms, Sridatta V. Teerdhala, Emily Fitzgerald, Ori Z. Chalom, Kushol Gupta, Mohamad‐Gabriel Alameh, Drew Weissman, Anh D. Le, Michael J. Mitchell   +15 more
wiley   +1 more source

The influence of helicopter tail rotor parameters on RCS

Hangkong gongcheng jinzhan
High requirements have been placed on the stealth performance of armed helicopters during wartime missions，in order to reduce the probability of the helicopter being found during the task，based on geometric optics method and consistent diffraction theory，
ZHAO Qijun
doaj   +1 more source

Resolving Heterogeneity of Targeted Lipid Nanoparticles Through Solution‐Based Biophysical Analyses

Advanced Materials, EarlyView.
AF4‐UV‐DLS‐MALS‐SAXS resolves previously inaccessible targeted lipid nanoparticle (tLNP) subpopulations that differ in size, shape, and composition. Correlation of subpopulation‐resolved biophysical properties with in vivo RNA delivery reveals that targeted placental transfection is associated with distinct tLNP subpopulations rather than ensemble ...
Hannah C. Geisler, Hannah C. Safford, Ajay S. Thatte, Marshall S. Padilla, Elisa Battistini, Hannah M. Yamagata, Violet M. Ullman, Alex Chan, Benjamin E. Nachod, Anushka Agrawal, Maxwell B. Watkins, Jesse B. Hopkins, Andrew Tsourkas, Kushol Gupta, Michael J. Mitchell   +14 more
wiley   +1 more source

Effect of multi-frequency parametric excitations on the dynamics of on-board rotor-bearing systems

, 2020
In the transportation domain such as automotive turbochargers and aircraft turbines, the vibrations of on-board rotors are induced not only by the mass unbalance excitation but also by various movements of their support. The dynamics of an on-board rotor
Y. Briend, M. Dakel, E. Châtelet, Marie-Ange Andrianoely, R. Dufour, S. Baudin   +5 more
semanticscholar   +1 more source

Numerical Continuation Applied to Nonlinear Rotor Dynamics

, 2016
Besides the synchronous oscillations due to unbalance, high-speed rotors in oil film bearings are known to show whirl/whip instabilities which exhibit various types of subsynchronous oscillations.
A. Boyaci
semanticscholar   +1 more source

Dynamic Mechanical Loading Modulates Extracellular Vesicle Production and Cargo in Meniscus Fibrochondrocytes

Advanced Materials Interfaces, EarlyView.
Dynamic mechanical loading of outer meniscus fibrochondrocytes increases extracellular vesicle (EV) yield and alters EV composition. When applied to progenitor cells, these mechanically primed EVs modulate the expression of matrix‐related genes.
Catherine Cheung, Zizhao Li, Sung‐Han Jo, Se‐Hwan Lee, Il Keun Kwon, Jina Ko, Su Chin Heo   +6 more
wiley   +1 more source

Failure Analysis and Optimization of the Rotor System in a Diesel Turbocharger for Rotor Speed-Up Test

Advances in Mechanical Engineering, 2014
During turbocharger rotor speed-up tests, the sensor installed in the compressor greatly affects the rotor dynamics. The effect of the floating bearing stiffness coefficient on the critical rotational speeds and the shaft dynamic response due to the ...
Liming Zhai, Yongyao Luo, Zhengwei Wang, Xin Liu   +3 more
doaj   +1 more source

Dynamics of the fermion-rotor system

Journal of High Energy Physics
A bstract We explore the dynamics of the fermion-rotor system, a simple impurity model in d = 1 +1 dimensions consisting of a collection of purely right-moving fermions interacting with a quantum mechanical rotor ...
Loladze, V, Okui, T, Tong, D
openaire   +3 more sources

Negotiating in a Foreign Land: Understanding the Curious Interactions Between Intracellular Mitochondria and Internalized Nanoparticles

Advanced Materials Interfaces, EarlyView.
Therapeutic nano‐drug delivery systems interact with cellular mitochondria in a multitude of ways. While the complexity of such interactions disrupts the mitochondrial electron transport chain and increases reactive oxygen species production, thereby contributing to nanoparticle toxicity, they also present unique theranostic opportunities in diseases ...
Sourav Bhattacharjee
wiley   +1 more source