Results 91 to 100 of about 1,478,859 (296)
Geospatial images in the acquisition of spatial knowledge for wayfinding
Journal of Spatial Information Science, 2012 Geospatial images, such as maps and aerial photographs, are important sources of spatial knowledge that people use for wayfinding. The rapid development of geodata acquisition and digital graphics has recently led to rather complete geographic coverage ...
Pyry Kettunen +4 more
doaj +1 more source
Multiparty Routing: Secure Routing for Mixnets
CoRR, 2017 Anonymous communication networks are important building blocks for online privacy protection. One approach to achieve anonymity is to relay messages through multiple routers, where each router shuffles messages independently. To achieve anonymity, at least one router needs to be honest.
Fatemeh Shirazi +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
The secret is to follow your nose: route path selection and angularity [PDF]
, 2001 This paper presents the results of an experiment in which route-choice decisions made by subjects at road-junctions are recorded. It will then demonstrate that a route can be expressed as the sum of the individual decisions made or as the sum of all ...
Conroy Dalton, R., Dalton, Ruth
core
Conceptualising Heritage Routes for Tourism: The Miracle of the Roses
International Journal of Religious Tourism and PilgrimageIn this article, a preliminary exploratory study is undertaken to cover a lesser researched topic in the tourism literature concerning the conceptualisation of heritage-based routes.
Isilda Leitão, Carlos Fernandes
doaj +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Huli yanjiu, 2020 The outcomes and related nursing care of children with Clostridium difficile infection（CDI） after faecal microbiota transplantation （FMT） by ascending and descending routes were reviewed.It was pointed out that both ascending routes and descending routes
WANG Lu, LI Dan, ZHANG Ting
doaj
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source