Results 71 to 80 of about 3,264,220 (298)
What’s in it for me? Incentive-compatible route coordination of crowdsourced resources [PDF]
With the recent trend in crowdsourcing, i.e., using the power of crowds to assist in satisfying demand, the pool of resources suitable for GeoPresence-capable systems has expanded to include already roaming devices, such as mobile phones, and moving ...
Bassem, Christine, Bestavros, Azer
core +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Arricchimento semantico del turismo alpino
Semantic enrichment of alpine tourism Ontological enrichment from semantic Web finds its own achievement in tourism information, mostly those related to alpine world.
Eliseo Clementini, Francesco Bartoli
doaj +2 more sources
Routing for manufacturability [PDF]
The impact of spot defects on the susceptibility for electrical failure of a net is analyzed. Based on this analysis, a general routing cost function is presented, in which the manufacturability of a net is taken into account in conjunction with the traditional routing objectives.
Xue, H., Huijbregts, E.P., Jess, J.A.G.
openaire +2 more sources
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Background/Objectives: We generated a novel recombinant Vibrio cholerae ghost (rVCG)-based subunit vaccine incorporating the A1 subunit of cholera toxin (CTA1) and a multiepitope Chlamydia trachomatis (CT) antigen (MECA) derived from five chlamydial ...
Fnu Medhavi +5 more
doaj +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
AUGMENTED REALITY OF STREET ART ROUTE FOR TOURISM, THAILAND [PDF]
Augmented Reality (AR) has been identified as a powerful tool for enhacing the tourism experience. It enables the visualization of historical attractions, cultural narratives, and educational content, and fostering deeper engagement with destinations ...
Numtip TRAKULMAYKEE* +3 more
doaj +1 more source

