Results 81 to 90 of about 1,478,859 (296)

Arricchimento semantico del turismo alpino

GEOmedia, 2010
Semantic enrichment of alpine tourism Ontological enrichment from semantic Web finds its own achievement in tourism information, mostly those related to alpine world.
Eliseo Clementini, Francesco Bartoli
doaj  

IMPROVING THE ORGANIZATION OF PASSENGER SERVICE ON THE ROUTE BY USING BUSES OF DIFFERENT CAPACITY

Вестник СибАДИ, 2019
Introduction. The authors propose to use a rational distribution of buses, taking into account their passenger capacity and the hours of the day, in order to optimize the operation of the rolling stock (RS) on the route.
I. M. Ryabovbov, R. Ya. Kashmanov
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Electrification of Urban Transport. Basic Stages in Creating Electric Buses Fleet

Механика машин, механизмов и материалов, 2018
The paper is of an analytical nature and is devoted to the systematization of approaches that take place in the tasks of creating an urban fleet of electric buses.
Vladimir B. Algin
doaj  

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Investigations on car emissions under the urban traffic conditions with the influence on Timişoara air quality

Transport, 2013
Poor air quality, a high traffic level and environmental noise as well as traffic congestion and greenhouse gases emissions require establishing measures, necessary to achieve an environmentally-friendly urban habitat.
Arina Negoiţescu, Adriana Tokar
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Alaska, Atlin, and the Yukon: White Pass and Yukon Route: [PDF]

, 1923
Title from cover. 1-5-23--Map, p. 44.

core  

A compreensão dos movimentos dos leitores em documentos www

InfoDesign: Brazilian Journal of Information Design, 2004
Este estudo objetiva identificar os movimentos dos leitores no espaço virtual e, para tanto, está estruturado como sendo uma viagem através do ambiente da Rede Mundial de computadores (www).
María González de Cossío
doaj