Results 81 to 90 of about 3,264,220 (298)

The secret is to follow your nose: route path selection and angularity [PDF]

open access: yes, 2001
This paper presents the results of an experiment in which route-choice decisions made bysubjects at road-junctions are recorded. It will then demonstrate that a route can be expressedas the sum of the individual decisions made or as the sum of all ...
Dalton, Ruth
core  

Multiparty Routing: Secure Routing for Mixnets

open access: yesCoRR, 2017
Anonymous communication networks are important building blocks for online privacy protection. One approach to achieve anonymity is to relay messages through multiple routers, where each router shuffles messages independently. To achieve anonymity, at least one router needs to be honest.
Fatemeh Shirazi   +3 more
openaire   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Applications of polymers in intraocular drug delivery systems

open access: yesOman Journal of Ophthalmology, 2017
We are entering a new era of ophthalmic pharmacology where new drugs are rapidly being developed for the treatment of anterior and posterior segment of the eye disease.
Ali Mohammed Alhalafi
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Geodesic survey and modernization of a route as the task of optimization

open access: yesGeodesy and Cartography, 2014
Inwentaryzacja istniejącej tras y wymaga wyznaczenia krzywej aproksymującej w wyniku optymalizacji realizowanej metodą najmniejszych kwadratów (TLSM). Analiza funkcji celu LSM wykazała, że jest ona kwadratem odległości Mahalanobisa w przestrzeni poprawek.
Nowak Edward
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Electrification of Urban Transport. Basic Stages in Creating Electric Buses Fleet

open access: yesМеханика машин, механизмов и материалов, 2018
The paper is of an analytical nature and is devoted to the systematization of approaches that take place in the tasks of creating an urban fleet of electric buses.
Vladimir B. Algin
doaj  

A multicriterial mathematical model for creating vehicle routes to transport goods / Transporto priemonių maršrutų prekėms vežti daugiakriterinis matematinis modelis /

open access: yesTransport, 2011
The article describes modelling a vehicle route to transport goods and discusses models for determining vehicle routes for a single depot and more vehicles. Above all, the paper defines a mathematical model for determining a vehicle route for more depots,
Jaroslav Kleprlík   +2 more
doaj   +1 more source

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