Results 61 to 70 of about 3,264,220 (298)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A Scalable Low-Cost-UAV Traffic Network (uNet)

, 2016
This article proposes a new Unmanned Aerial Vehicle (UAV) operation paradigm to enable a large number of relatively low-cost UAVs to fly beyond-line-of-sight without costly sensing and communication systems or substantial human intervention in individual
Devasia, Santosh, Lee, Alexander
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

THEORETICAL JUSTIFICATION OF EXPONENTIAL DISTRIBUTION LAW OF DISTANCES BETWEEN STOPS OF CITY PUBLIC TRANSPORT [PDF]

Avtomobilʹnyj Transport (Harʹkov), 2012
The paper presents the results of investigation of relation bitween the trip distance on stops location on the route between places of attraction. Theoretical justification of the use fulness of exponential distribution with the shift parameter for ...
Gorbachov, P., Makarychev, O. , Svichynskyi, S.   +2 more
doaj  

Traffic Accident Blackspot Identification and Ambulance Fastest Route Mobilization Process for the City of Surakarta [PDF]

, 2012
Quickly and precisely treatment in traffic accident is one way to avoid the risk of death victims. Therefore, it's necessary to determine the fastest route from the traffic accident locations to the nearest hospital.
Budiharto, U. (Utoyo), Saido, A. P. (Agus), Syafi’i, S. (Syafi’i)   +2 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Reducing Packet Overhead in Mobile IPv6

, 2012
Common Mobile IPv6 mechanisms, Bidirectional tunneling and Route optimization, show inefficient packet overhead when both nodes are mobile. Researchers have proposed methods to reduce packet overhead regarding to maintain compatible with standard ...
Zolfagharnasab, Hooshiar
core   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Qualitative Assessment of Urban Design Elements from the Old and New Urban Fabrics in Aïn-Beïda (Algeria) [PDF]

Urbanism. Arhitectura. Constructii
The effects of the physical environment on people's active behaviour have been a central topic over the last decade, particularly in urban design, public health, and transportation.
Ines Soltani, Rachid Hadef
doaj