Results 111 to 120 of about 3,803,647 (352)

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

open access: yesMolecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef   +10 more
wiley   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Editorial on: Habits: plasticity, learning and freedom

open access: yesFrontiers in Human Neuroscience, 2015
Javier eBernacer   +2 more
doaj   +1 more source

Beyond cytotoxic T cells: reprogrammed regulatory T cells help facilitate response to dual checkpoint blockade

open access: yesMolecular Oncology, EarlyView.
Rolig, Peng, and colleagues have shed new light on how dual blockade of PD1 and LAG3 enhances antitumor immunity. They found that response to immunotherapy with anti‐PD1 + anti‐LAG3 was associated with reprogramming of canonically suppressive CD4+ regulatory T cells to an inflammatory state.
Tullia C. Bruno, Anthony R. Cillo
wiley   +1 more source

Satellite lifetime routine user's manual [PDF]

open access: yes
A FORTRAN coded computer program which determines secular variations in mean orbital elements of earth satellites and the lifetime of the orbit is described.
Everett, H. U., Myler, T. R.
core   +1 more source

Incorporating Naloxone Education Into Routine Primary Care [PDF]

open access: yes, 2018
Opioid overdoses are a growing public health concern in Vermont and nationwide. Naloxone can save the life of someone who overdoses, if those around them know how to use it.
Goldberg, Eli
core   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

open access: yesMolecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella   +18 more
wiley   +1 more source

DID THE CHANGES MADE TO THE 2022-2024 CODE OF POINTS IN TRAMPOLINE GYMNASTICS CHANGE THE SCORE OF THE GYMNASTS?

open access: yesScience of Gymnastics Journal
e evaluation rules for trampoline gymnastics were revised by the technical committee post-Tokyo 2020 Olympics, notably affecting the qualifying round. Previously, only four elements were considered for difficulty points in the first routine, but now all
Sercin Kosova, Merve Koca Kosova
doaj   +1 more source

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