Results 111 to 120 of about 3,578,337 (334)

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

Molecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo, Yoshihiro Mezawa, Zixu Wang, Ahmet Acar, Yasuhiko Ito, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Yataro Daigo, Takuya Shirakihara, Akira Orimo   +11 more
wiley   +1 more source

L’invention des routines

Espace populations sociétés, 2015
Speaking of routines, in social sciences easily carries connotations related to alienation. Routines, it is said, come from the fact that individuals and households, depend on heavy macro-social time constraints that impose their mechanical time on their
Frédéric de Coninck
doaj   +1 more source

THE EFFECTS OF TRANSPOSITION OF THE DAILY ROUTINE ON THE RHYTHM OF TEMPERATURE VARIATION [PDF]

, 1905
Robert Gibson
openalex   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

Violência, crime e polícia: o que os favelados dizem quando falam desses temas? Violence, crime and police: what do people who live in slums say when they talk about these subjects?

Sociedade e Estado, 2007
O artigo baseia-se em duas pesquisas qualitativas em favelas cariocas, especialmente em uma de suas atividades, aproximadamente 50 horas de dinâmica com 15 grupos focais (envolvendo 150 moradores de mais de 40 favelas).
Luiz Antonio Machado da Silva, Márcia Pereira Leite   +1 more
doaj   +1 more source

ROUTINE NUTRITIONAL TESTS FOR THE IDENTIFICATION OF DERMATOPHYTES [PDF]

, 1957
Lucille K. Georg, LaVerne B. Camp
openalex   +1 more source

Obstetric violence in the daily routine of care and its characteristics

Revista Latino-Americana de Enfermagem, 2018
Objective: to analyze the scientific production on obstetric violence by identifying and discussing its main characteristics in the routine care for the pregnant-puerperal cycle.
Danúbia Mariane Barbosa Jardim, C. Modena   +1 more
semanticscholar   +1 more source

Device calibration impacts security of quantum key distribution

, 2011
Characterizing the physical channel and calibrating the cryptosystem hardware are prerequisites for establishing a quantum channel for quantum key distribution (QKD).
C. H. Bennett, Carlos Wiechers, Christoffer Wittmann, Christoph Marquardt, D. Gottesman, Dominique Elser, Gerd Leuchs, Lars Lydersen, Nitin Jain, Vadim Makarov   +9 more
core   +1 more source

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

Propuesta de esquemas de tratamiento antituberculosis basados en la susceptibilidad A isoniacida y rifampicina

Revista Peruana de Medicina Experimental y Salud Pública
Objetivo. Elaborar esquemas de tratamiento para tuberculosis de acuerdo con sus perfiles de susceptibilidad a isoniacida (H) y rifampicina (R). Materiales y métodos. Un total de 12 311 aislamientos de M.
Alberto Mendoza-Ticona, David AJ Moore, Valentina Alarcón, Frine Samalvides, Carlos Seas   +4 more
doaj