Results 51 to 60 of about 1,607,761 (243)
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Routinization in the Context of Equation and Inequality Concepts: A Case Study
Ankara Üniversitesi Eğitim Bilimleri Fakültesi DergisiThis study aims to reveal the structure of learning as routinization by providing empirical examples. The participation of a high school student in discourse in task situations involving systems of equations and inequalities was examined in terms of ...
Gönül Yazgan Sağ +2 more
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Exploring the Daily Lives of People on Methadone Maintenance Treatment: An Occupational Perspective
Societies, 2016 A qualitative study was undertaken with five people on methadone maintenance treatment (MMT) to better understand their experiences and daily routines.
Katrina Warren +3 more
doaj +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
21st Century Televisuality? Golden Ages and Collateral Damage in Industry Stress Research
Media and CommunicationThis article examines how the innovations of, and fallout from, the post-1980s US multichannel cable era both prefigured and were transformed by the 21st-century online platform streaming era.
John T. Caldwell
doaj +1 more source
Archives of Academic Emergency Medicine, 2018 Introduction:Â Hemothorax is one of the most prevalent injuries caused by thoracic traumas. Early detection and treatment of this injury is of utmost importance in prognosis of the patient, but there are still controversial debates on the diagnostic ...
Vafa Rahimi-Movaghar +8 more
doaj +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Archives of Academic Emergency Medicine, 2018 Introduction:Â The potential benefit of ultrasonography for detection of thoracic bone fractures has been proven in various surveys but no comprehensive conclusion has been drawn yet; therefore, the present study aimed to conduct a thorough meta-analytic
Mahmoud Yousefifard +8 more
doaj +1 more source