Results 51 to 60 of about 47,726 (265)

CERP: Cooperative and Efficient Routing Protocol for Wireless Sensor Networks

open access: yesSensors, 2023
Wireless sensor networks (WSNs), constrained by limited resources, demand routing strategies that prioritize energy efficiency. The tactic of cooperative routing, which leverages the broadcast nature of wireless channels, has garnered attention for its ...
Nesrine Atitallah   +4 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

A Comprehensive Survey on Vehicular Networking: Communications, Applications, Challenges, and Upcoming Research Directions

open access: yesIEEE Access, 2022
Nowadays, advanced communication technologies are being utilized to develop intelligent transportation management and driving assistance. Through the ability to exchange traffic and infotainment information between road infrastructure and vehicles ...
Nehad Hameed Hussein   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Lightweight Hybrid Cryptography Algorithm for Wireless Body Area Sensor Networks Using Cipher Technique

open access: yesComputer Assisted Methods in Engineering and Science
Wireless Body Area Networks (WBANs) are based on connected and dedicated sensor nodes for patient monitoring in the healthcare sector. The sensor nodes are implanted inside or outside the patient’s body for sensing the vital signs and transmitting the ...
Aizaz Raziq   +4 more
doaj   +1 more source

A Kalman Filter Based Hybrid Routing Protocol for Efficient Vehicle Connectivity and Traffic Management

open access: yesTransport and Telecommunication, 2022
The geographic routing protocols in Vehicular Ad Hoc Networks (VANETs) are contemplated as most efficacious protocols. Though, such types of protocols communicate a huge quantity of data that influence the network connectivity negatively.
Punia Divya, Kumar Rajender
doaj   +1 more source

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