Results 61 to 70 of about 565,488 (365)

Exact algorithms for the clustered vehicle routing problem [PDF]

open access: yes, 2014
This study presents new exact algorithms for the Clustered Vehicle Routing Problem (CluVRP). The CluVRP is a generalization of the Capacitated Vehicle Routing Problem (CVRP), in which the customers are grouped into clusters.
Vigo, Daniele   +8 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Multi Period Routing and Scheduling optimization Model for Home health Care Problem [PDF]

open access: yesMuṭāli̒āt-i Mudīriyyat-i Ṣan̒atī, 2018
Home health care services have a key importance in modern societies. Most organizations working in this area in Iran use the traditional procedure to plan and manage medical staff and determine the arrangement of visiting patients.
Seyed Mohammad Taghi Fatemi Ghomi   +2 more
doaj   +1 more source

Experimenting with Routing Protocols in the Data Center: An ns-3 Simulation Approach

open access: yesFuture Internet, 2022
Massive scale data centers (MSDC) have become a key component of current content-centric Internet architecture. With scales of up to hundreds of thousands servers, conveying traffic inside these infrastructures requires much greater connectivity ...
Leonardo Alberro   +4 more
doaj   +1 more source

Dynamic routing in circuit-switched non-hierarchical networks [PDF]

open access: yes, 1989
This thesis studies dynamic routing in circuit-switched non-hierarchical networks based on learning automata algorithms. The application of a mathematical model for a linear reward penalty algorithm is explained.
Eshragh, Nadereh
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Smart Site Diversity for a High Throughput Satellite System with Software-Defined Networking and a Virtual Network Function

open access: yesFuture Internet, 2020
High Throughput Satellite (HTS) systems aim to push data rates to the order of Terabit/s, making use of Extremely High Frequencies (EHF) or free-space optical (FSO) in the feeder links. However, one challenge that needs to be addressed is that the use of
Gandhimathi Velusamy, Ricardo Lent
doaj   +1 more source

A Hybrid MFCM-PSO Approach for Tree-Based Multi-Hop Routing Using Modified Fuzzy C-Means in Wireless Sensor Network

open access: yesIEEE Access, 2023
A wireless sensor network (WSN) collects data from various monitoring systems using small sensor nodes (SNs). The WSN analyses and sends found data to the BS.
Neetu Sikarwar, Ranjeet Singh Tomar
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Parent and PHY Selection in Slot Bonding IEEE 802.15.4e TSCH Networks

open access: yesSensors, 2021
While IEEE 802.15.4e Time-Slotted Channel Hopping (TSCH) networks should be equipped to deal with the hard wireless challenges of industrial environments, the sensor networks are often still limited by the characteristics of the used physical (PHY) layer.
Glenn Daneels   +5 more
doaj   +1 more source

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