Results 81 to 90 of about 565,488 (365)

Privacy-enhanced social-network routing

open access: yes, 2011
This work is supported by the UK Engineering and Physical Sciences Research Council and the Technology Strategy Board as part of the Privacy Value Networks project, EP/G002606/1.Opportunistic networking—forwarding messages in a disconnected mobile ad hoc
Parris, Iain Siraj   +3 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

A DTN routing scheme for quasi-deterministic networks with application to LEO satellites topology [PDF]

open access: yes, 2012
We propose a novel DTN routing algorithm, called DQN, specifically designed for quasi-deterministic networks with an application to satellite constellations.
Dubois, Emmanuel   +11 more
core   +1 more source

Bilingualism and the Single route / Dual route debate [PDF]

open access: yes, 2022
The debate between single and dual route accounts of cognitive processes has been generated predominantly by the application of connectionist modeling techniques to two areas of psycholinguistics. This paper draws an analogy between this debate and bilingual language processing.
openaire   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

A Kalman Filter Based Hybrid Routing Protocol for Efficient Vehicle Connectivity and Traffic Management

open access: yesTransport and Telecommunication, 2022
The geographic routing protocols in Vehicular Ad Hoc Networks (VANETs) are contemplated as most efficacious protocols. Though, such types of protocols communicate a huge quantity of data that influence the network connectivity negatively.
Punia Divya, Kumar Rajender
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Performance study of end-to-end traffic-aware routing [PDF]

open access: yes, 2006
There has been a lot research effort on developing reactive routing algorithms for mobile ad hoc networks (MANETs) over the past few years. Most of these algorithms consider finding the shortest path from source to destination in building a route ...
Ould-Khaoua, M.   +2 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

PSAR: Power-Source-Aware Routing in ZigBee Networks [PDF]

open access: yes, 2012
ZigBee is a recent wireless networking technology built on IEEE 802.15.4 standard and designed especially for low-data rate and low-duty cycle applications such as home and building automation and sensor networks.
Korpeoglu, Ibrahim   +3 more
core   +1 more source

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