Results 61 to 70 of about 1,615,898 (335)

Research on the Data Technology of LKJ-15 System

open access: yesKongzhi Yu Xinxi Jishu, 2018
Considering the present application status of LKJ infrastructure data, and the Chinese railway transportation demands such as the current railway line construction and operation adjustment, and the application of long locomotive routing, data modeling ...
FANG Guanghua
doaj  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

The forwarding indices of graphs - a survey [PDF]

open access: yesOpuscula Mathematica, 2013
A routing \(R\) of a connected graph \(G\) of order \(n\) is a collection of \(n(n-1)\) simple paths connecting every ordered pair of vertices of \(G\).
Jun-Ming Xu, Min Xu
doaj   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Evaluación del tiempo de recuperación de fallas para LSP L1VPN sobre redes GMPLS

open access: yesTecnura, 2012
Nowadays network failure is a common problem that is caused, to certain extent, by various factors such as the number of devices involved in a link, the quality of these devices, their geographical location, and environmental conditions among others ...
Octavio Salcedo   +2 more
doaj  

A Heuristic Angular Clustering Framework for Secured Statistical Data Aggregation in Sensor Networks

open access: yesSensors, 2020
Clustering in wireless sensor networks plays a vital role in solving energy and scalability issues. Although multiple deployment structures and cluster shapes have been implemented, they sometimes fail to produce the expected outcomes owing to different ...
Lalitha Krishnasamy   +5 more
doaj   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

open access: yesFEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

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