Results 61 to 70 of about 1,611,892 (260)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

The forwarding indices of graphs - a survey [PDF]

open access: yesOpuscula Mathematica, 2013
A routing \(R\) of a connected graph \(G\) of order \(n\) is a collection of \(n(n-1)\) simple paths connecting every ordered pair of vertices of \(G\).
Jun-Ming Xu, Min Xu
doaj   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Evaluación del tiempo de recuperación de fallas para LSP L1VPN sobre redes GMPLS

open access: yesTecnura, 2012
Nowadays network failure is a common problem that is caused, to certain extent, by various factors such as the number of devices involved in a link, the quality of these devices, their geographical location, and environmental conditions among others ...
Octavio Salcedo   +2 more
doaj  

A Heuristic Angular Clustering Framework for Secured Statistical Data Aggregation in Sensor Networks

open access: yesSensors, 2020
Clustering in wireless sensor networks plays a vital role in solving energy and scalability issues. Although multiple deployment structures and cluster shapes have been implemented, they sometimes fail to produce the expected outcomes owing to different ...
Lalitha Krishnasamy   +5 more
doaj   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

open access: yesFEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini   +13 more
wiley   +1 more source

Smart Site Diversity for a High Throughput Satellite System with Software-Defined Networking and a Virtual Network Function

open access: yesFuture Internet, 2020
High Throughput Satellite (HTS) systems aim to push data rates to the order of Terabit/s, making use of Extremely High Frequencies (EHF) or free-space optical (FSO) in the feeder links. However, one challenge that needs to be addressed is that the use of
Gandhimathi Velusamy, Ricardo Lent
doaj   +1 more source

A machine learning-based branch and price algorithm for a sampled vehicle routing problem [PDF]

open access: hybrid, 2021
Nikolaus Furian   +3 more
openalex   +1 more source

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