Results 91 to 100 of about 67,204 (291)

Impact of Mutational Status on Intracellular Effects of Cell‐Permeable CaaX Peptides in Pancreatic Cancer Cells

open access: yesChemBioChem, EarlyView.
This work deals with intracellular effects of cell‐permeable CaaX‐peptides, designed to influence prenylated proteins like KRas. The results show that after CaaX‐1 treatment, not only KRas expression and signaling are specifically altered in mutated pancreatic cancer cells, but also plasma membrane localization of KRas is affected.
Merlin Klußmann   +2 more
wiley   +1 more source

The purification and identification of antioxidants and dipeptidyl peptidase IV inhibitory peptides from whey protein hydrolysates

open access: yesFood Bioengineering, Volume 1, Issue 3-4, Page 298-306, December 2022., 2022
Whey protein was enzymatically hydrolyzed using an ultrahigh‐pressure synergistic enzymolysis method. The identified amino acid sequences were then synthesized, and their antioxidants and DPP‐IV inhibitory activities were determined. Whey protease hydrolysates could potentially be expected to be successfully commercially developed as functional ...
Zheng Yuanrong, Pang Jiakun, Liu Zhenmin
wiley   +1 more source

Investigation of Host-Guest Stability Constants of Calix[n]arenes Complexes with Aromatic Molecules by RP-HPLC Method [PDF]

open access: bronze, 2003
R. Baudry   +4 more
openalex   +1 more source

Bioorthogonal Postlabeling Reveals Nuclear Localization of a Highly Cytotoxic Half‐Sandwich Ir(III) Tetrazine Complex in Live Cells

open access: yesChemBioChem, EarlyView.
This study reports the synthesis of five tetrazine‐coordinated, half‐sandwich iridium complexes and extensively describe their reactivity. Live cell fluorescent bioorthogonal labeling reveals the nuclear tropism of the most cytotoxic complex. Intracellular imaging of anticancer metallodrugs often relies on prelabeling with organic fluorophores, which ...
Alfonso Annunziata   +6 more
wiley   +1 more source

Development and validation of RP-HPLC and RP-UPLC methods for quantification of erythropoietin formulated with human serum albumin

open access: yesJournal of Pharmaceutical Analysis, 2012
Rapid and sensitive reverse phase high performance liquid chromatography (RP–HPLC) and ultra performance liquid chromatography (UPLC) methods with UV detection for quantification of erythropoietin (EPO) in presence of human serum albumin (HSA) as a ...
Shaligram S. Rane   +3 more
doaj  

Rapid HPLC determination of ciprofloxacin, ofloxacin, and marbofloxacin alone or in a mixture

open access: yesResults in Chemistry, 2023
A simple, sensitive, and accurate chromatography (RP-HPLC) method for simultaneous estimation of Ciprofloxacin, Ofloxacin, and Marbofloxacin in their combined pharmaceutical dosage form or individually. The HPLC separation was achieved on a Hypersil (C18,
Kh. Elgendy   +3 more
doaj  

Self‐Assembly of Cholane–Phenanthrene–Cholane Trimers for Light‐Harvesting Supramolecular Systems

open access: yesChemBioChem, EarlyView.
The self‐assembly of phosphodiester‐linked cholane–phenanthrene–cholane trimers is described. The morphology of the formed nanostructures depends on the phenanthrene isomer used and on the cooling rate during the assembly process leading to nanosheets, worm‐like structures, or nanotubes.
Edouard Ehret   +4 more
wiley   +1 more source

Isolation and characterization of antioxidant peptides from oyster (Crassostrea rivularis) protein enzymatic hydrolysates

open access: yesFood Science &Nutrition, Volume 11, Issue 1, Page 261-273, January 2023., 2023
Five obtained peptides exhibited high radical scavenging activities in the following order: F5 > F3 > F1 > F2 > F4.; F5 has the highest activities for DPPH‐IC50 was 21.75 μg/mL, hydroxyl‐IC50 was 18.75 μg/mL, and Superoxide‐IC50 was 11.00 μg/mL and the reducing power was 2.54 OD700.; F5 had the highest antioxidant activity and not only prevented the ...
Hui Huang   +9 more
wiley   +1 more source

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