Results 101 to 110 of about 59,227 (260)

Estimation and Validation of Geftinib by Rp- HPLC

open access: yes
Abstract A simple, rapid, precise and accurate Rp-Hplc method was developed and validated for the determination of Geftinib citrate, in bulk and pharmaceutical dosage form. The separation is achieved on RP-HPLC using a PDA detector by incorporation of enpower 2 software with a flow rate of 1.0ml/min using a mixture of Methanol and water (15:85%
Shaheen Sultana   +3 more
openaire   +1 more source

Use of predictive tools for the analysis of bioactive compounds in crocus SATIVUS L. flowers

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Crocus sativus L. (saffron) flowers have high bioactive potential because of their content of crocins, safranal and phenolic compounds. The development of predictive models based on near‐infrared (NIR) spectroscopy and partial least squares regression to estimate the antioxidant capacity of saffron flower, evaluated using oxygen ...
Manuel Piqueras‐García   +4 more
wiley   +1 more source

Unambiguous analytical separation and improved syntheses of [11C]acetate and [11C]acetoacetate

open access: yesEJNMMI Radiopharmacy and Chemistry
Background [11C]Acetate and [11C]acetoacetate are PET radiotracers widely used to assess oxidative metabolism and ketone body utilization, respectively. This study aimed to establish robust, high-yield syntheses of both tracers using a GE TRACERlab FX2 C
Karsten Bamminger   +4 more
doaj   +1 more source

Chemical Ionization Mass Spectrometry: Fundamental Principles, Diverse Applications, and the Latest Technological Frontiers

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The review examines the evolution of chemical ionization mass spectrometry (CI‐MS), a technique developed in 1966 by Field and Munson. CI is a soft‐ionization method that produces more intense molecular ions with less fragmentation than electron ionization (EI).
Malvika Dutt   +4 more
wiley   +1 more source

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág   +5 more
wiley   +1 more source

Mechano‐Optical Behavior During Processing of PolyCannabidiol Terephthalate: A Biobased, High‐Tg Thermoplastic

open access: yesPolymer Engineering &Science, EarlyView.
Hemp‐extracted cannabidiol is used as‐is to synthesize polycannabidiol terephthalate, a non‐food, bio‐based engineering plastic with Tg 156°C and stretchability up to 1100%. Process–structure–property maps from real‐time drying and mechano‐optical analysis inform future industrial film production for a range of applications currently served by PET ...
Henry D. Davis   +4 more
wiley   +1 more source

Chemical diversity and phylogenetic insights into Hawaiian ʻākia (Wikstroemia) species used in traditional fishing practices

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Traditional fishing with plant‐based piscicides is a global practice in decline, facing increasing restrictions. We investigated the chemical diversity of endemic Wikstroemia species historically used to stun or poison fish in Hawaiʻi. Using 1‐H‐NMR, principal component analysis, targeted HPLC, and target‐capture sequencing, we characterized compounds ...
Louise Winther   +10 more
wiley   +1 more source

Seedling resistance and chemical defenses against Psylliodes chrysocephala: the roles of seed age and sinapinic acid in Sinapis alba and Brassica napus

open access: yesPest Management Science, EarlyView.
The cabbage stem flea beetle (Psylliodes chrysocephala) is a major pest of winter oilseed rape (Brassica napus). We tested B. napus and Sinapis alba seedlings for feeding resistance and underlying chemical defenses. S. alba was least damaged, while metabolite profiles revealed resistance‐linked compounds, highlighting breeding potential for insect ...
Daniel Rüde   +4 more
wiley   +1 more source

Effects of timed LED regimes on tomato plant traits, performance of two‐spotted spider mites, and predatory mites (Phytoseiulus persimilis)

open access: yesPest Management Science, Volume 81, Issue 4, Page 2300-2311, April 2025.
Light‐emitting diode (LED)‐based treatments for enhancing crop production and pest management have primarily focused on continuous treatments. This study, using Tetranychus urticae and Phytoseiulus persimilis, demonstrates that the timing of LED supplementation is crucial for designing integrated pest management strategies that improve both plant ...
Patrice Savi   +5 more
wiley   +1 more source

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