Results 101 to 110 of about 97,740 (305)

Design of a Fluorescent Boronic Acid‐Functionalized Pyranoflavylium Receptor to Host and Release Diol‐Rich Bioactive Analytes in a pH‐Dependent Manner

open access: yesChemFoodChem, EarlyView.
This work presents a pH‐responsive ON–OFF fluorescent system based on a novel pyranoflavylium dye functionalized with a boronic acid receptor. The receptor exhibits a markedly higher affinity for the catechol‐containing polyphenol (+)‐catechin than for conventional diol‐rich molecules such as glucose and lactic acid.
Beatriz Senra   +5 more
wiley   +1 more source

Chromatography of wine [PDF]

open access: yes, 2013
The objectives of the review are the collection, concise description and evaluation of the various chromatographic technologies applied for the separation and quantitative determination of macro- and microcomponents present in ...
Cserháti, Tibor, Szőgyi, Mária
core  

Methyl on the Bridge: 2‐Methyl Propellane as Precursor for 1,3‐Substituted 2‐Methylated Bicyclo[1.1.1]Pentanes

open access: yesChemistry – A European Journal, EarlyView.
The synthesis of 2‐methyl propellane and its conversion to various 1,2‐ and 1,2,3‐di‐ and trisubstituted bicyclopentanes is reported. Abstract Bicyclo[1.1.1]pentanes (BCPs) have emerged as isosteric replacements for mono‐ and para‐substituted benzene rings in medicinal and materials applications, involving substitution at the BCP bridgehead (1,3 ...
Sean R. Verschaeve   +4 more
wiley   +1 more source

Chemical Ligation of Backbone N‐hydroxylated Peptides

open access: yesChemistry – A European Journal, EarlyView.
Peptide backbone N‐hydroxylation enables sequence‐agnostic fragment ligation via hydroxamate O‐acyl capture and O→N acyl transfer in water. Broad tolerance of sterically demanding nucleophilic residues is observed, and reductive N─O cleavage restores the native amide bond.
Natalia Cano‐Sampaio   +1 more
wiley   +1 more source

Evaluation of l-dopa, proximate composition with in vitro anti-inflammatory and antioxidant activity of Mucuna macrocarpa beans: A future drug for Parkinson treatment

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2017
Objective: To investigate L-3, 4-dihydroxyphenylalanine (l-dopa, anti-Parkinson drug), anti-inflammatory activity, proximate nutritional composition and antioxidant potential of Mucuna macrocarpa (M. macrocarpa) beans.
Chetan Aware   +5 more
doaj   +1 more source

Separation and Purification of Lipase Inhibitory Peptide from Fermented Milk by Lactobacillus plantarum Q180

open access: yesFood Science of Animal Resources, 2020
In this study, we separated and purified lipase inhibitory peptide from fermented milk by Lactobacillus plantarum Q180 with the aim of developing a new functional anti-lipase activity yogurt product. L. plantarum 180 was inoculated into 10% reconstituted
Seulki Kim, Sang-Dong Lim
doaj   +1 more source

Phosphorescent Iridium Hydrazinonicotinic Acid (HYNIC) Complexes That Bind to Prostate Specific Membrane Antigen: Potential Photodynamic Therapy of Prostate Cancer

open access: yesChemistry – A European Journal, EarlyView.
A phosphorescent iridium(III) complex has been prepared with a 6‐hydrazinonicotinic acid (HYNIC) ligand tethered to a lysine‐ureido‐glutamatic acid pharmacophore, which binds to an enzyme, called prostate‐specific membrane antigen (PSMA), which is overexpressed in prostate cancer.
La'El Kimchi   +6 more
wiley   +1 more source

Greening Reversed-Phase Liquid Chromatography Methods Using Alternative Solvents for Pharmaceutical Analysis

open access: yesMolecules, 2018
The greening of analytical methods has gained increasing interest in the field of pharmaceutical analysis to reduce environmental impacts and improve the health safety of analysts.
Moussa Yabré   +3 more
doaj   +1 more source

A Validated Reversed-Phase HPLC Method for the Determination of Atorvastatin Calcium in Tablets [PDF]

open access: yes, 2014
A Reversed-Phase Liquid Chromatographic (RP-LC) assay method was developed for the quantitative determination of atorvastatin calcium in the presence of its degradation products.
Ferello, L.   +5 more
core  

Total Syntheses of Agelamadin F and (±)‐Tauroacidin A, Enabled by NaClO2‐Mediated Coupling Reactions of Oroidin and Amines

open access: yesChemistry – A European Journal, EarlyView.
Total syntheses of agelamadin F and (±)‐tauroacidin A were achieved by sodium chlorite (NaClO2)‐mediated oxidative C─N coupling. Nine C15–N–amino acid‐substituted oroidin derivatives were successfully prepared to demonstrate the applicability and versatility of this oxidative coupling reaction.
Ryosuke Hirozumi   +3 more
wiley   +1 more source

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