Results 121 to 130 of about 59,105 (258)

Peptide‐based antibacterial nanoplatforms: Design principles, stimuli‐regulated behaviors, and applications

Responsive Materials, EarlyView.
Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan, Chenlong Zhou, Shuaikang Yang, Zhenduo Chen, Guanghui Zhao, Qi Tang, Haoyu Yan, Feng Li, Xi Ma   +8 more
wiley   +1 more source

Modular Molecular Design and Self‐Assembled Nanostructures of Saccharide‑Appended Cyclic Dipeptides for Glycosidase‑Responsive Supramolecular Hydrogels

Small, EarlyView.
Saccharide‐appended cyclic dipeptides are designed and developed as building blocks for glycosidase‐responsive supramolecular hydrogels. Their aqueous self‐assembly enables β‐galactosidase‐triggered gel‐to‐sol and neuraminidase‐triggered sol‐to‐gel transition systems, highlighting their potential as glycosidase‐responsive soft materials for biomedical ...
Shintaro Sugiura, Ryuta Tanaka, Sayuri L. Higashi, Aya Shibata, Koichiro M. Hirosawa, Kenichi G. N. Suzuki, Masato Ikeda   +6 more
wiley   +1 more source

Synergistic and Antagonistic Effects of Chemical Pollutants and Parasitic Fungi on Cyanobacterial Metabolism

Environmental Toxicology, EarlyView.
ABSTRACT Freshwater ecosystems are increasingly impacted by anthropogenic pollutants, including the widely used herbicide metolachlor (MET) and cigarette butt (CB) litter. Parasites represent an additional biotic stressor that can modulate pollutant effects on their hosts.
Erika Berenice Martínez‐Ruiz, Jutta Fastner, Stephanie Spahr, Justyna Wolinska   +3 more
wiley   +1 more source

Determination of 5-Hydroxymethylfurfural Content in Marketed Honey: A Modified RP-HPLC Method. [PDF]

Int J Anal Chem
Adu-Brimpong B, Brobbey AA, Adu JK, Addotey JN, Abeka MK, Attah IY.   +5 more
europepmc   +1 more source

Structural basis of regioselective double halogenation of the β‐carboline tryptoline by the single‐component halogenase AetF

Acta Crystallographica Section D, EarlyView.
A structure of the flavin‐dependent single‐component tryptophan halogenase AetF bound to the non‐native tricyclic substrate tryptoline reveals a binding pose analogous to l‐tryptophan that directs C6‐first halogenation. Product analysis identifies 6,8‐dibromotryptoline as the final product.Flavin‐dependent halogenases (FDHs) offer a biocatalytic route ...
Simon Bork, Hendrik J. Horstmeier, Bjarne Scharkowski, Hartmut H. Niemann   +3 more
wiley   +1 more source

A Stability-Indicating RP-HPLC Method for Simultaneous Determination of Triclabendazole and Levamisole in Oral Suspension Formulation. [PDF]

Int J Anal Chem
Elbashir AA, Hamid KMM.
europepmc   +1 more source

Nutritional composition of pollen stores in managed bees across European agro‐ecosystems reveals species‐specific differences but limited pesticide effects

Ecological Entomology, EarlyView.
In the pollen stores of three bee species deployed across 128 European sites, bumble bees harboured lower lipid content and higher protein‐to‐lipid ratios than honey bees and mason bees. Toxicity‐weighted pesticide risk did not alter protein‐to‐lipid ratios, but higher risk was associated with reduced protein and lipid content in the pollen stores of ...
Antoine Gekière, Clément Tourbez, Maryse Vanderplanck, Tomasz Kiljanek, Guillaume Ghisbain, Elif Kardas, Irene Bottero, Marie‐Pierre Chauzat, Elena Cini, Francesca Corvucci, Joachim R. de Miranda, Gennaro Di Prisco, Christophe Dominik, Francesca V. Grillenzoni, Simon Hodge, Anina Knauer, Marion Laurent, Vicente Martínez‐López, Risto Raimets, Janine M. Schwarz, Deepa Senapathi, Giorgia Serra, Giovanni Tamburini, Dimitry Wintermantel, Mark J. F. Brown, Matthias Albrecht, Cecilia Costa, Pilar De la Rúa, Alexandra‐Maria Klein, Marika Mänd, Simon G. Potts, Maj Rundlöf, Oliver Schweiger, Jane C. Stout, Denis Michez   +34 more
wiley   +1 more source

Development of an AQbD-guided sustainable RP-HPLC method for simultaneous quantification of saracatinib and rapamycin in lipid-polymer hybrid nanocarriers. [PDF]

RSC Adv
Angolkar M, Paramshetti S, Patil D, K M AS, Osmani RAM, Gangadharappa HV, Fatease AA, Alamri AH, Hani U.   +8 more
europepmc   +1 more source

A new branch of mammalian vitamin B6 metabolism: AKR1C‐mediated conversion of pyridoxal to pyridoxine and 4‐pyridoxolactone

The FEBS Journal, EarlyView.
Pyridoxal 5′‐phosphate (PLP) homeostasis relies on salvage enzymes, yet key metabolic branches remain undefined. We identify AKR1C isozymes as previously undescribed contributors that convert pyridoxal into pyridoxine or 4‐pyridoxolactone through reductase and dehydrogenase activities.
Nayu Kito, Yasuyuki Kitaura, Kyoka Iino, Kazuya Toriumi, Hyunah Noh, Naoya Ogawa, Makoto Arai, Hisashi Hemmi, Tomokazu Ito   +8 more
wiley   +1 more source

Eco-Conscious RP-HPLC Method for Concurrent Quantification of Assay and Dissolution Testing of Methocarbamol and Diclofenac Potassium in Tablet Formulations. [PDF]

Int J Anal Chem
Ouni H, Alminderej FM, Salem ME, Saleh SM, Al Kamaly O, Mohamed MA.   +5 more
europepmc   +1 more source