Results 91 to 100 of about 59,105 (258)

Validated RP‐HPLC–UV Method for the Quantitative Analysis and Stability Evaluation of Amoxicillin in Paediatric Gummy Tablets

ELECTROPHORESIS, EarlyView.
A validated RP‐HPLC–UV method was successfully applied for amoxicillin determination in gummy tablets. The method is useful for an accurate amoxicillin content determination in paediatric gummies and was applied to study the stability profile of the drug, evaluated over 6 months under storage conditions.
Samuele Bonafè, Anna Imbriano, Cinzia Pagano, Anna Migni, Elisa Bianconi, Laura Mercolini, Luana Perioli, Roccaldo Sardella   +7 more
wiley   +1 more source

Application of HPLC for detection of sildenafil/tadalafil in marketed honey in Oman

International Journal of Secondary Metabolite
Honey adulteration allegedly with phosphodiesterase-5 (PDE-5) inhibitors including sildenafil, and tadalafil is a common and dangerous practice. This study aimed to develop a procedure to detect the presence of common adulterants namely sildenafil and ...
Mohammad Jawaıd Akhtar, Hameda Hamood Al Dhakhri, Shah Alam Khan, Sumit Pannu, Fatema Alqassabi, Israa Alrasbi, Dhuha Alhinai, Salha Al Salty, Shaima Al Balushi   +8 more
doaj   +1 more source

A Novel HILIC‐UPLC‐DAD‐MS/MS Method for the Analysis of Mycosporine‐Like Amino Acids and Their Quantification in Diverse Algae

ELECTROPHORESIS, EarlyView.
The separation of selected mycosporine‐like amino acids and two biosynthetic precursors, in total 13 compounds, by HILIC‐UPLC is described for the first time. With an analysis time of only 5 min, it surpasses all currently known methods for analysis of these promising natural products.
Armin Oberosler, Anastasiia Fedorova, Ignacio Zegri, Fabian Hammerle, Michael Zwerger, Thomas Werner, Markus Ganzera   +6 more
wiley   +1 more source

Optimized iCIEF Fractionation Enables Deep Profiling of Antibody Drug Conjugate Charge Heterogeneity

ELECTROPHORESIS, EarlyView.
This study developed and optimized an iCIEF fractionation method to characterize ADC charge variants. The optimized approach enabled stable separation, identification of major PTMs, and drug‐load distributions across light and heavy chains. ABSTRACT Antibody drug conjugates (ADCs) are a novel class of therapeutic drugs that combine selectivity of an ...
Eunju Jang, Qunying Zhang, Paul M. Thomas   +2 more
wiley   +1 more source

Biomass‐derived hydrochars as eco‐friendly adsorbents for wastewater treatment applications

Environmental Progress &Sustainable Energy, EarlyView.
Abstract Emerging organic pollutants (EOPs), such as diethyl phthalate (DEP), bisphenol A (BPA), and methylene blue (MB), are only partially removed in conventional wastewater treatment plants. This study assesses hydrochars produced by hydrothermal carbonization (HTC) of spruce bark (SB), vine shoots (VSs), and wheat straw (WSs) for removing three ...
Emanuel Gheorghita Armanu, Sara Ribeirinho‐Soares, Christian Eberlein, Hermann J. Heipieper, Irina Volf, Olga C. Nunes, Olívia Salomé G. P. Soares   +6 more
wiley   +1 more source

Strategies for Identification and Mitigation of Sanguinarine in Mustard Oil Adulterated by Argemone—A Comprehensive Review

Food Chemistry International, EarlyView.
Sanguinarine, a toxic alkaloid present in argemone, can lead to epidemic dropsy or chronic diseases through DNA intercalation and immune system suppression. Regulatory efforts face challenges due to economic motivations for adulteration as well as technical, social, and infrastructure barriers.
Gururaj Pejavara Narayana, Subhangi Panigrahi, Suresh Kumar Kalakandan, Hema Vincent, Ashish Rawson   +4 more
wiley   +1 more source

Advances in protein–polyphenol complexation: Unraveling mechanisms, modulation, and functional outcomes

Food Biomacromolecules, EarlyView.
Abstract Polyphenolic compounds have attracted increasing market demand and extensive attention due to their potential health benefits and bioactivities. Meanwhile, proteins are widely used in the food industry for their nutritional and functional properties. However, the application of proteins in the food industry is often limited by challenges, such
Fang Li, Ziming Xu, Tian Zhao, Gongshuai Song, Danli Wang, Tinglan Yuan, Ling Li, Jinyan Gong   +7 more
wiley   +1 more source

Development and characterization of a nutritionally rich traditional fermented product aktori

Food Biomacromolecules, EarlyView.
Graphical representation of development of traditional fermented Aktori. The figure illustrates the development of aktori, a traditional food fermented with curd, which demonstrates enhanced nutritional and functional properties, along with probiotic characteristics.
Shambhvi, Mahesh Gupta
wiley   +1 more source

Novel RP-HPLC method development and validation for precise quantification of prochlorperazine maleate in pharmaceutical dosage forms

Journal of Applied Pharmaceutical Research
Background: Prochlorperazine Maleate, a piperazine phenothiazine derivative, exhibits strong antiemetic and antipsychotic properties. However, existing analytical methods for its quantification in pharmaceutical formulations often face limitations ...
Nikhil Shrisunder, Prashant Kumar Dhakad, Ritu Gilhotra   +2 more
doaj   +1 more source

Simultaneous Quantification of Phenolic Compounds and Capsaicinoids in Chili Peppers Using Ultra‐High Performance Liquid Chromatography‐Tandem Mass Spectrometry

Food Safety and Health, EarlyView.
A UHPLC‐MS/MS method was developed to simultaneously quantify four capsaicinoids and 19 phenolic compounds, the key bioactive constituents in chili peppers. It exhibits high sensitivity, low matrix effects, excellent accuracy, and precision, enabling reliable detection in chili samples.
Shaoyun Wu, Xue Feng, Haixiao Ma, Yinfeng Zhao, Zhenying Sun, Meiling Zhang, Zehua Ke, Jing Qiu, Yongzhong Qian, Guiqiao Liu, Rui Weng   +10 more
wiley   +1 more source