Results 101 to 110 of about 67,204 (291)

Separation and Quantification of Tiliroside from Plant Extracts by SPE/RP-HPLC [PDF]

, 2003
Renata Nowak
openalex   +1 more source

Discovery and In Vitro Reconstitution of Closoxazole Biosynthesis from Pyxidicoccus fallax

ChemBioChem, EarlyView.
The myxobacterium Pyxidicoccus fallax is found to be a producer of benzoxazole‐containing natural products named closoxazoles. In vitro studies with the biosynthetic enzymes reveal new insights into the reaction mechanism for closoxazole formation.
Lucia Lernoud, Rimonda Jakob, Lars Warnick, Marie Luisa Marx, Lea Winand   +4 more
wiley   +1 more source

Development and validation of analytical method for the estimation of lamivudine in rabbit plasma

Journal of Pharmaceutical Analysis, 2011
Lamivudine has been widely used in the treatment of HIV disease. A reliable, sensitive reversed phase high performance liquid chromatography (RP-HPLC) method was developed and validated for lamivudine in rabbit plasma.
Akhilesh Vikram Singh, Lila K. Nath, Nihar R. Pani   +2 more
doaj  

Exploiting SpyTag/SpyCatcher Technology To Design New Artificial Catalytic Copper Proteins

ChemBioChem, Accepted Article.
Designing artificial metal binding sites within a protein is challenging since amino acid residues need to be placed in desired positions in the final construct and the use of non‐natural amino acids is difficult. The alternative approach of directing the insertion of artificial metal coordination systems presents the difficulty of grafting such site ...
Silvia Gentili, Francesca Miglioli, Valentina Borghesani, Gloria Spagnoli, Denise Bellotti, Davide Cavazzini, Remo Guerrini, Maurizio Remelli, Giovanni Maestri, Simone Ottonello, Angelo Bolchi, Matteo Tegoni   +11 more
wiley   +1 more source

In vitro assessment of varying peptide surface density on the suppression of angiogenesis by micelles displaying αvβ3 blocking peptides

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 111, Issue 2, Page 343-353, February 2023., 2023
Abstract Ligand targeted therapy (LTT) is a precision medicine strategy that can selectively target diseased cells while minimizing off‐target effects on healthy cells. Integrin‐targeted LTT has been developed recently for angiogenesis‐related diseases.
Neha Phani Bhushan, Trevor Stack, Evan A. Scott, Kenneth R. Shull, Benjamin Mathew, Divya Bijukumar   +5 more
wiley   +1 more source

Novel RP-HPLC method development and validation for precise quantification of prochlorperazine maleate in pharmaceutical dosage forms

Journal of Applied Pharmaceutical Research
Background: Prochlorperazine Maleate, a piperazine phenothiazine derivative, exhibits strong antiemetic and antipsychotic properties. However, existing analytical methods for its quantification in pharmaceutical formulations often face limitations ...
Nikhil Shrisunder, Prashant Kumar Dhakad, Ritu Gilhotra   +2 more
doaj   +1 more source

First Steps toward the Design of Peptides that Influence the Intracellular Palmitoylation Machinery

ChemBioChem, EarlyView.
Herein, DC peptides consisting of the cell‐penetrating peptide sC18* and a Asp–His–His–Cys (DHHC) motif derived from human ZDHHC palmitoyltransferase are highlighted. DC peptides demonstrate high cellular internalization into various cellular models, exert cytotoxic effects against cancerous cells, and alter the function and localization of known ...
Katharina Stillger, Eric Platz‐Baudin, Florian Friedland, Melina Ruppel, Coco‐Louisa Sticker, Anne Bodenhausen, Erik Noetzel, Ines Neundorf   +7 more
wiley   +1 more source

Study of Different Types of Milk Protein Analysis Using Reverse Phase Chromatography RP-HPLC

Scientific Papers Animal Science and Biotechnologies, 2023
Milk proteins have been extensively studied for over 90 years. Proteomics and associated technologies have the potential to facilitate an advanced knowledge of the proteins in milk. Proteomics allows detection, identification and characterization of milk
Camelia Hodoşan, Lucica Nistor, Gratziela Buhaciu, Daniela Ianițchi, Florența Vilău, Ioana Dușescu   +5 more
doaj  

Mitochondria‐Catalyzed Activation of Anticancer Prodrugs

ChemCatChem, EarlyView.
Prodrug C is a water soluble, monomeric compound accumulating in mitochondria of cancer cells, where it is activated in the reaction with mitochondrial H2O2. The activation leads to the release of camptothecin that causes cell cycle arrest in G2 phase and cancer cell death.
Michael Raucheisen, Dina Attia, Marlies Körber, Alejandra Aroca Crevillén, Andrés Hidalgo, Frank Beierlein, Petra Imhof, Andriy Mokhir   +7 more
wiley   +1 more source

Study on the Characterization and Degradation Pattern of Circular RNA Vaccines Using an HPLC Method

Chemosensors
Circular RNA (circRNA) vaccines have attracted increasing attention due to their stable closed-loop structures and persistent protein expression ability.
Feiran Cheng, Ji Li, Chaoying Hu, Yu Bai, Jianyang Liu, Dong Liu, Qian He, Qiuheng Jin, Qunying Mao, Zhenglun Liang, Miao Xu   +10 more
doaj   +1 more source