Results 111 to 120 of about 134,980 (300)

Development of RP-HPLC methods for the analysis of melatonin alone and in combination with sleep-enhancing dietary supplements [PDF]

open access: yesPharmacia
Melatonin, a hormone produced by the pineal gland, is widely recognized for its role in regulating sleep-wake cycles. With the increasing prevalence of sleep disorders, melatonin supplements have gained popularity as a natural remedy.
Lily Peikova   +3 more
doaj   +3 more sources

In Vivo and In Vitro Evaluation of PTeCA (1H‐Pyrrole‐2,3,4,5‐Tetracarboxylic Acid) in Hair Matrix as a Marker for Oxidative Cosmetic Treatment

open access: yesDrug Testing and Analysis, EarlyView.
A total of 3378 self‐reported treated and untreated hair samples were analyzed for PTCA and PTeCA by LC‐MS/MS. Moreover, their in vitro formation was assessed in 225 untreated hair by different cosmetic treatments with and without oxidative agents. Data suggest that PTeCA could be a reliable marker for oxidative cosmetic treatments in hair.
Sara Casati   +8 more
wiley   +1 more source

Studies on Log Po/w of Quinoxaline di-N-Oxides: A Comparison of RP-HPLC Experimental and Predictive Approaches

open access: yesMolecules, 2011
As reported in our previous papers, a series of quinoxaline-2-carboxamide 1,4-di-N-oxide derivatives were synthesized and studied as anti-tuberculosis agents. Here, the capability of the shake-flask method was studied and the retention time (expressed as
James A. Platts   +7 more
doaj   +1 more source

Total Synthesis of rac‐Keramamine C Enabled by Intrinsic H‐Bond‐Induced Conformational Fixation of Amides

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
The total synthesis of the manzamine alkaloid keramamine C (2) in its racemic form was achieved in 5 steps, with ring‐closing metathesis as the key step. The metathesis is strongly improved by an intramolecular H‐bond‐induced conformational fixation of the amide bond, inducing close proximity of the terminal double bonds in the precursor molecule.
Jana Ganzmann   +4 more
wiley   +1 more source

Goat and cow casein derived ingredients and their interactions with iron : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Food Technology, Massey University, Palmerston North, New Zealand [PDF]

open access: yes, 2017
The objective of this study was to gain a fundamental understanding of how goat casein micelles and the products of casein proteins behave when fortified with iron. Iron fortified skim milk was characterised by analysing the mass balance of micellar/non
Smialowska, Alice Małgorzata
core  

Chemical Syntheses of 3′ and 5′ Phosphorylated Oligonucleotides: An Overview

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
This review provides an overview of the various chemical methods employed in the synthesis of oligonucleotides bearing a phosphate group at their 3′ or 5′ end. Notably, it presents modified phosphoramidites and supports developed for this purpose. Oligonucleotides (ON) with a phosphate monoester group at their 3′ or 5′ end have applications in many ...
Rémy Lartia
wiley   +1 more source

Anchoring of Surface Proteins to the Cell Wall of Staphylococcus aureus: sortase catalyzed in vitro transpeptidation reaction using LPXTG peptide and NH2-Gly3 substrates [PDF]

open access: yes, 2000
Staphylococcus aureus sortase anchors surface proteins to the cell wall envelope by cleaving polypeptides at the LPXTG motif. Surface proteins are linked to the peptidoglycan by an amide bond between the C-terminal carboxyl and the amino group of the ...
Faull, Kym F.   +3 more
core  

Validated RP‐HPLC–UV Method for the Quantitative Analysis and Stability Evaluation of Amoxicillin in Paediatric Gummy Tablets

open access: yesELECTROPHORESIS, EarlyView.
A validated RP‐HPLC–UV method was successfully applied for amoxicillin determination in gummy tablets. The method is useful for an accurate amoxicillin content determination in paediatric gummies and was applied to study the stability profile of the drug, evaluated over 6 months under storage conditions.
Samuele Bonafè   +7 more
wiley   +1 more source

Analytical Quality by Design-Guided Optimisation and Validation of a Short-Run Stability-Indicating Reverse-Phase Ultra-Fast Liquid Chromatography (RP-UFLC) Method for the Quantitation of Nonivamide. [PDF]

open access: yesBiomed Chromatogr
ABSTRACT Nonivamide (NON), a capsaicin analogue with similar pharmacological effects, is used in pain management, yet limited information exists on its accurate quantification by reverse‐phase liquid chromatography. A cost‐effective, efficient and precise RP‐HPLC method was developed, optimised using response surface methodology (central composite ...
Mahlangu P   +3 more
europepmc   +2 more sources

Biomass‐derived hydrochars as eco‐friendly adsorbents for wastewater treatment applications

open access: yesEnvironmental Progress &Sustainable Energy, EarlyView.
Abstract Emerging organic pollutants (EOPs), such as diethyl phthalate (DEP), bisphenol A (BPA), and methylene blue (MB), are only partially removed in conventional wastewater treatment plants. This study assesses hydrochars produced by hydrothermal carbonization (HTC) of spruce bark (SB), vine shoots (VSs), and wheat straw (WSs) for removing three ...
Emanuel Gheorghita Armanu   +6 more
wiley   +1 more source

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