Results 101 to 110 of about 134,980 (300)

Methyl on the Bridge: 2‐Methyl Propellane as Precursor for 1,3‐Substituted 2‐Methylated Bicyclo[1.1.1]Pentanes

Chemistry – A European Journal, EarlyView.
The synthesis of 2‐methyl propellane and its conversion to various 1,2‐ and 1,2,3‐di‐ and trisubstituted bicyclopentanes is reported. Abstract Bicyclo[1.1.1]pentanes (BCPs) have emerged as isosteric replacements for mono‐ and para‐substituted benzene rings in medicinal and materials applications, involving substitution at the BCP bridgehead (1,3 ...
Sean R. Verschaeve, Mariana Gomes Manso, Tibo Van Eeckhoorn, Mark E. Light, Bruno Linclau   +4 more
wiley   +1 more source

Synthesis and antimicrobial evaluation of two peptide LyeTx I derivatives modified with the chelating agent HYNIC for radiolabeling with technetium-99m

Journal of Venomous Animals and Toxins including Tropical Diseases, 2016
Background Current diagnostic methods and imaging techniques are not able to differentiate septic and aseptic inflammation. Thus, reliable methods are sought to provide this distinction and scintigraphic imaging is an interesting option, since it is ...
Leonardo Lima Fuscaldi, Daniel Moreira dos Santos, Natália Gabriela Silva Pinheiro, Raquel Silva Araújo, André Luís Branco de Barros, Jarbas Magalhães Resende, Simone Odília Antunes Fernandes, Maria Elena de Lima, Valbert Nascimento Cardoso   +8 more
doaj   +1 more source

Reverse Phase-high-performance Liquid Chromatography (RP-HPLC) Analysis of Globin Chains from Human Erythroid Cells. [PDF]

Bio Protoc, 2021
Chalumeau A, Frati G, Magrin E, Miccio A.   +3 more
europepmc   +1 more source

Analysis of imidazoles and triazoles in biological samples after MicroExtraction by packed sorbent [PDF]

, 2017
This paper reports the MEPS-HPLC-DAD method for the simultaneous determination of 12 azole drugs (bifonazole, butoconazole, clotrimazole, econazole, itraconazole, ketoconazole, miconazole, posaconazole, ravuconazole, terconazole, tioconazole and ...
Bellagamba, Giuseppe, Campestre, Cristina, Carradori, Simone, Celia, Christian, De Luca, Elisa, Di Marzio, Luisa, Guglielmi, Paolo, Locatelli, Marcello, Menta, Sergio, Zengin, Gokhan   +9 more
core   +3 more sources

Chemical Ligation of Backbone N‐hydroxylated Peptides

Chemistry – A European Journal, EarlyView.
Peptide backbone N‐hydroxylation enables sequence‐agnostic fragment ligation via hydroxamate O‐acyl capture and O→N acyl transfer in water. Broad tolerance of sterically demanding nucleophilic residues is observed, and reductive N─O cleavage restores the native amide bond.
Natalia Cano‐Sampaio, Juan R. Del Valle   +1 more
wiley   +1 more source

Aspects of proteolysis in cheese : a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy in Food Technology at Massey University [PDF]

, 1994
The purpose of the present study was to elaborate methods for the detailed examination of proteolysis pathways in cheese (reviewed in Chapter 1) and to demonstrate their usefulness.
Coker, Christina June
core  

Controlled assembly of SNAP-PNA-fluorophore systems on DNA templates to produce fluorescence resonance energy transfer [PDF]

, 2014
The SNAP protein is a widely used self-labeling tag that can be used for tracking protein localization and trafficking in living systems. A model system providing controlled alignment of SNAP-tag units can provide a new way to study clustering of fusion ...
Bader A. N., Bannwarth M., Brun M. A., Campos C., Carrion-Vazquez M., Chakrabarti R., Dadon Z., Daguer J. P., Diaz-Mochon J. J., Donovan C., Feldkamp U., Gautier I., Gholami Z., Gorska K., Gronemeyer T., Harris J. L., Haruki H., Hermanson G. T., Hinner M. J., Huang K.-T., Hussain A. F., Hutchins B. M., Johnsson K., Johnsson N., Juillerat A., Jung D., Kamiya M., Kampmeier F., Kazane S. A., Keppler A., Keppler A., Keppler A., Keppler A., Komatsu T., Lakowicz J. R., Lin M. Z., Lo P. K., Lovrinovic M., Lu H., Maurel D., Menchise V., Niemeyer C. M., Niemeyer C. M., Niemeyer C. M., O’Hare H. M., Pianowski Z. L., Pin J. P., Pouchain D., Prencipe G., Quentin Hanley, Roloff A., Rothemund P. W. K., Rothlingshofer M., Rozners E., Runnels L. W., Sadhu K. K., Scheibe C., Scheibe C., Scheibe C., Seeman N. C., Spinelli N., Sun X., Svensen N., Urbina H. D., Weber G., Weber G., Winssinger N., Yeow E. K. L., Zahra Gholami, Zolmajd-Haghighi Z.   +69 more
core   +1 more source

Phosphorescent Iridium Hydrazinonicotinic Acid (HYNIC) Complexes That Bind to Prostate Specific Membrane Antigen: Potential Photodynamic Therapy of Prostate Cancer

Chemistry – A European Journal, EarlyView.
A phosphorescent iridium(III) complex has been prepared with a 6‐hydrazinonicotinic acid (HYNIC) ligand tethered to a lysine‐ureido‐glutamatic acid pharmacophore, which binds to an enzyme, called prostate‐specific membrane antigen (PSMA), which is overexpressed in prostate cancer.
La'El Kimchi, Emily R. McGowan, Katherine A. Morgan, Jonathan M. White, Trevor A. Smith, Stacey E. Rudd, Paul S. Donnelly   +6 more
wiley   +1 more source

Biologically active compounds from selected aphyllophorales mycelial cultures [PDF]

, 2014
The obtained results confirm the hypothesis that mycelial cultures of domestic species of aphyllophorales are able to accumulate biologically active metabolites.Uzyskane wyniki wskazują, że przebadane kultury mycelialne krajowych gatunków grzybów ...
Firlej, Anna, Muszyńska, Bożena, Sułkowska-Ziaja, Katarzyna   +2 more
core   +2 more sources

Total Syntheses of Agelamadin F and (±)‐Tauroacidin A, Enabled by NaClO2‐Mediated Coupling Reactions of Oroidin and Amines

Chemistry – A European Journal, EarlyView.
Total syntheses of agelamadin F and (±)‐tauroacidin A were achieved by sodium chlorite (NaClO2)‐mediated oxidative C─N coupling. Nine C15–N–amino acid‐substituted oroidin derivatives were successfully prepared to demonstrate the applicability and versatility of this oxidative coupling reaction.
Ryosuke Hirozumi, Yuta Kudo, Yuko Cho, Mari Yotsu‐Yamashita   +3 more
wiley   +1 more source