Results 81 to 90 of about 134,980 (300)

RP-HPLC-DAD-MS Analysis and Butyrylcholinesterase Inhibitory Activity of Extracts

Natural Product Communications, 2015
High-performance liquid chromatography (HPLC) coupled to a diode-array detector (DAD) and electrospray ionization mass spectrometry (MS) was applied for the separation and identification of phenolic compounds in the n -hexane, ethyl acetate and methanol ...
Jósquia S Barbosa, Verônica M Almeida, Rosilene M Marçal, Alexsandro Branco   +3 more
doaj   +1 more source

Simultaneous RP-HPLC-DAD determination of dansyl amino acids in chemically treated human hair

Macedonian Journal of Chemistry and Chemical Engineering, 2018
A simple, rapid and reliable RP-HPLC-DAD method for the analysis of 19 amino acids in the protein hydrolysate of chemically treated hair is developed. The pre-column dansylation and RP-HPLC separation were optimized and peak resolution was improved as ...
Pece Sherovski, Marina Stefova, Natasha Ristovska   +2 more
doaj   +1 more source

Determination of the concentration of major active anti-emetic constituents within commercial ginger food products and dietary supplements [PDF]

, 2017
Introduction: Studies suggest that the bioactive compounds contained within the rhizome of ginger (Zingiber officinale) could exert a beneficial effect on the symptoms of several chronic conditions (e.g.
Isenring, Elisabeth A., Lohning, Anna E., Marx, Wolfgang   +2 more
core   +1 more source

Nano‐Gs Protein Peptidomimetics: Rational Design of Gα C‐Terminus‐Derived Peptides Mimicking Key Components of Gs‐β2AR Interactions

Angewandte Chemie International Edition, EarlyView.
G protein‐coupled receptors (GPCRs) are major therapeutic targets. Modulating GPCR activity through intracellular sites is evolving. A structure‐ and computation‐assisted approach generated small G protein‐derived peptidomimetics targeting the intracellular binding crevice of the β2 adrenergic receptor mimicking features of the full G protein.
Phuong Thu Tran, Mia Danielsen, Johanna K. S. Tiemann, Passainte Ibrahim, Søren G. F. Rasmussen, Xavier Kubiak, Hossein Batebi, Charlène Gadais, Steven Ballet, Peter W. Hildebrand, Daniel Sejer Pedersen, Jesper Mosolff Mathiesen   +11 more
wiley   +1 more source

Recent developments in the rapid analysis of plants and tracking their bioactive constituents [PDF]

, 2009
Natural products chemistry has witnessed many new developments in the last 5 years like extractions with subcritical water and ionic liquids, LC/HRMS and LC/SPE/cryo-NMR, UHPLC, TLC/MS, MS-based preparative HPLC, comprehensive chromatography (GC × GC, LC
Beek, T.A., van, Claassen, F.W., Dapkevicius, A., Exarchou, V., Jeurissen, S.M.F., Klift, E.J.C., van der, Koleva, I., Tetala, K.K.R.   +7 more
core   +2 more sources

In Situ Construction of Imidazopyridinium Fluorescent Labels for Bioconjugation

Angewandte Chemie International Edition, EarlyView.
Chromophore engineering of isoquinoline aldehydes generates TICT‐based fluorogenic dyes for in situ labeling of diverse (bio)molecules with large Stokes shifts compatible with cell imaging. ABSTRACT Simple, efficient transformations of fluorogenic nature that proceed under biocompatible conditions without the formation of byproducts are of high ...
Dongchen Du, László Albert, Milan Weitzel, Linda E. Eijsink, Elena R. Cotroneo, Dennis Marzin, Felipe Opazo, Nadja A. Simeth   +7 more
wiley   +1 more source

RP-HPLC method for simultaneous quantification of free and total thiol groups in native and heat aggregated whey proteins

MethodsX, 2020
Disulfide formation of whey proteins during heat treatment via thiol oxidation is important with regard to techno-functional properties. Due to the formation of other oxidation products than disulfides, the decrease in free thiol concentration is not ...
Franziska Kurz, Claudia Hengst, Ulrich Kulozik   +2 more
doaj   +1 more source

Non-canonical proteolytic activation of human prothrombin by subtilisin from Bacillus subtilis may shift the procoagulant\ue2\u80\u93anticoagulant equilibrium toward thrombosis [PDF]

, 2017
Blood coagulation is a finely regulated physiological process culminating with the factor Xa (FXa)-mediated conversion of the prothrombin (ProT) zymogen to active -thrombin (T).
Acquasaliente, Laura, Artusi, Ilaria, De Filippis, Vincenzo, Frasson, Roberta, Peterle, Daniele, Pontarollo, Giulia   +5 more
core   +1 more source

Analysis of Dapsone by RP-HPLC

International Journal For Multidisciplinary Research
A Simple,Precise and accurate RP-HPLC method was developed and validated for the analysis of Dapsone in ...
openaire   +1 more source

A Modular Mechanistic In Silico Model for In Vitro Transcription Process Yield and Product Quality Prediction

Biotechnology and Bioengineering, EarlyView.
ABSTRACT In vitro transcription (IVT) plays a critical role in the manufacture of mRNA vaccines and therapeutics. Optimizing mRNA yield and ensuring product quality, such as capping efficiency and integrity, are essential but mechanistically complex. This study presents a modular mechanistic model of the IVT process to advance scientific understanding ...
Keqi Wang, Keilung Choy, Eli Reiser, Jinxiang Pei, Hua Zheng, Aparajita Dasgupta, Fuqiang Cheng, Guogang Dong, Bhanu Chandra Mulukutla, Joshua Mannheimer, Carolyn Huang, Hooman Farsani, Wei Xie   +12 more
wiley   +1 more source