Results 61 to 70 of about 134,980 (300)

Development and validation of an high-performance liquid chromatographic, and a ultraviolet spectrophotometric method for determination of Ambroxol hydrochloride in pharmaceutical preparations

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2013
A high-performance liquid chromatographic (HPLC) and ultraviolet (UV) methods were developed and validated for the quantitative determination of Ambroxol hydrochloride (AMH) in pharmaceutical dosage form.
Selvadurai Muralidharan   +2 more
doaj   +1 more source

De Novo Design and Directed Evolution Refinement of Mirror‐Image Protein Binders Targeting Interleukin‐4

open access: yesAdvanced Science, EarlyView.
This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu   +7 more
wiley   +1 more source

Study on the Characterization and Degradation Pattern of Circular RNA Vaccines Using an HPLC Method

open access: yesChemosensors
Circular RNA (circRNA) vaccines have attracted increasing attention due to their stable closed-loop structures and persistent protein expression ability.
Feiran Cheng   +10 more
doaj   +1 more source

Stability of Mycotoxins in Individual Stock and Multi-Analyte Standard Solutions

open access: yesToxins, 2020
Standard solutions of mycotoxins prepared in RP HPLC solvents from neat standards are usually used for analytical method development. Multi-mycotoxin HPLC-MS/MS methods necessitate stability estimation for the wide spectrum of fungal metabolites.
Mariya Kiseleva   +3 more
doaj   +1 more source

A Validated Reversed-Phase HPLC Method for the Determination of Atorvastatin Calcium in Tablets [PDF]

open access: yes, 2014
A Reversed-Phase Liquid Chromatographic (RP-LC) assay method was developed for the quantitative determination of atorvastatin calcium in the presence of its degradation products.
Ferello, L.   +5 more
core  

Enzymatic DNA Reaction Networks for Orchestrating Stimuli‐Dependent Temporal Molecular Pulse

open access: yesAdvanced Science, EarlyView.
We present an enzymatic DNA reaction network (EDRN) that encodes nucleic‐acid targets in time, converting inputs into a universal strand and then into programmable transient fluorescence pulses. With time‐color multiplexing, EDRN enables single‐tube high‐plex nucleic acid detection and shows strong agreement with clinical sequencing across 32 specimens.
Jiayu Yang   +7 more
wiley   +1 more source

Retention Modelling of Phenoxy Acid Herbicides in Reversed-Phase HPLC under Gradient Elution

open access: yesMolecules, 2020
Phenoxy acid herbicides are used worldwide and are potential contaminants of drinking water. Reversed phase high-performance liquid chromatography (RP-HPLC) is commonly used to monitor phenoxy acid herbicides in water samples.
Alessandra Biancolillo   +4 more
doaj   +1 more source

Modified bacterial reaction centers [PDF]

open access: yes, 1991
Pigments of borohydride-treated reaction centers of Rhodobacter sphaeroides R 26 and Rhodopseudomonas viridis were analyzed by HPLC with polychromatic detection. In both species, pigment composition and contents were unchanged.
A. Müller   +44 more
core   +1 more source

"Quantitative Analysis of Ritonavir Tablets by RP-HPLC"

open access: yesInternational Journal of Pharmaceutical Research and Applications
This study presents a comprehensive validation of a reverse-phase high-performance liquid chromatography (RP-HPLC) method for the quantitative determination of Ritonavir. The chromatographic separation was achieved using a Shimpack Solar C18 column (250 mm × 4.6 mm, 5 µm) in conjunction with a potassium buffer. The isocratic mobile phase consisted of a
Santosh P. Kumbhar   +5 more
openaire   +1 more source

Erasable FAP Targeted Spray‐On Probe for Fluorescence‐Guided Surgery

open access: yesAdvanced Science, EarlyView.
We present the first erasable spray‐on probe for fluorescence‐guided surgery. Following topical delivery, FAP‐FLASH550 targets fibroblast activation protein–expressing stromal cells, delineating tumor margins with high tumor‐to‐background ratios. A 365 nm UV light pulse rapidly erases fluorescent signals through triazene photodegradation and subsequent
Zachary Rabinowitz   +2 more
wiley   +1 more source

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