Results 1 to 10 of about 208,725 (182)

A constitutively active Gαi3 protein corrects the abnormal retinal pigment epithelium phenotype of Oa1-/- mice. [PDF]

, 2013
PurposeOcular Albinism type 1 (OA1) is a disease caused by mutations in the OA1 gene and characterized by the presence of macromelanosomes in the retinal pigment epithelium (RPE) as well as abnormal crossing of the optic axons at the optic chiasm.
Ahmedli, Novruz B, Farber, Debora B, Jiang, Meisheng, Wang, Ying, Young, Alejandra   +4 more
core   +27 more sources

Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD

Autophagy, 2022
In dry age-related macular degeneration (AMD), LCN2 (lipocalin 2) is upregulated. Whereas LCN2 has been implicated in AMD pathogenesis, the mechanism remains unknown.
Urvi Gupta, Sayan Ghosh, Callen T. Wallace, P. Shang, Ying Xin, A. Nair, M. Yazdankhah, Anastasia Strizhakova, M. Ross, Haitao Liu, S. Hose, N. Stepicheva, Olivia Chowdhury, M. Nemani, Vishnu Maddipatla, R. Grebe, Manjula Das, K. Lathrop, J. Sahel, J. Zigler, Jiang Qian, Arkasubhra Ghosh, Y. Sergeev, J. Handa, C. S. St Croix, D. Sinha   +25 more
semanticscholar   +1 more source

Hypoxia aggravates ferroptosis in RPE cells by promoting the Fenton reaction

Cell Death and Disease, 2022
Oxidative stress and hypoxia in the retinal pigment epithelium (RPE) have long been considered major risk factors in the pathophysiology of age-related macular degeneration (AMD), but systematic investigation of the interplay between these two risk ...
Y. Henning, Ursula Sarah Blind, Safa Larafa, J. Matschke, J. Fandrey   +4 more
semanticscholar   +1 more source

Skeletal and alveolar changes in conventional rapid palatal expansion (RPE) and miniscrew-assisted RPE (MARPE): a prospective randomized clinical trial using low-dose CBCT

BMC Oral Health, 2022
Background This prospective randomized clinical trial aimed to evaluate the immediate and short-term skeletal, dentoalveolar, and periodontal effects of rapid palatal expansion (RPE) and miniscrew-assisted RPE (MARPE) in adolescent and young adult ...
Joo-Hee Chun, Amanda Cunha Regal de Castro, Sun-Kyong Oh, Kyung-Ho Kim, Sung-Hwan Choi, L. Nojima, M. G. Nojima, Kee-Joon Lee   +7 more
semanticscholar   +1 more source

Peculiarities of the Norton conversions application when matching impedances with different transformation coefficients

Физика волновых процессов и радиотехнические системы, 2022
The paper studies the features and consequences of the use of Norton conversions in the process of broadband and narrowband matching of circuit impedances based on filter theory in cases with different transformation ratios.
Aleksander V. Baranov
doaj   +1 more source

Phase frequency characteristics evaluation for E-class devices output circuits

Физика волновых процессов и радиотехнические системы, 2022
Based on the unitarity of the E-class device circuit [S]-matrix, the phase frequency characteristics are estimated for the output circuit at any harmonic of the fundamental frequency.
Alexander V. Baranov
doaj   +1 more source

Shared Operation of a Barrage Jammer and Reference Signal Sources for Determining Ground-Based Radio Transmitters Operating via Geostationary Relay Satellites

Известия высших учебных заведений России: Радиоэлектроника, 2021
Introduction.  There  are  incidences  of  jamming  the  users  of  satellite  communication  systems,  who  apply  e.g. geostationary relay satellites, and the illegal use of such satellite resources.
R. D. Gall
doaj   +1 more source

Some Hints to Develop Particular Line Pipe Specification [PDF]

MATEC Web of Conferences, 2019
When procuring the carbon steel line pipe for pipeline project, frequently the purchaser refers to the international standards/specifications such as API SPEC 5L without any particular requirements.
Fandika Ardian
doaj   +1 more source

Nrf2 overexpression rescues the RPE in mouse models of retinitis pigmentosa

JCI Insight, 2021
Nrf2, a transcription factor that regulates the response to oxidative stress, has been shown to rescue cone photoreceptors and slow vision loss in mouse models of retinal degeneration (rd). The retinal pigment epithelium (RPE) is damaged in these models,
David M. Wu, Xuke Ji, Maryna V. Ivanchenko, Michelle Chung, Mary E. Piper, Parimal Rana, Sean K. Wang, Yunlu Xue, Emma R. West, Sophia Zhao, Hongbin Xu, Marcelo Cicconet, W. Xiong, C. Cepko   +13 more
semanticscholar   +1 more source

Features of the development of broadband frequency mixers with suppression of the mirror channel in the range frequencies 9–27 GHz

Физика волновых процессов и радиотехнические системы, 2020
The article is devoted to features of the development two types of broadband frequency mixers with image channel suppression in the frequency range 927 GHz.
Grigoriy A. Uglov, Yulia V. Belova
doaj   +1 more source