Results 91 to 100 of about 208,874 (328)

Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cells. [PDF]

, 2017
PurposeThe RPE cell line ARPE-19 provides a dependable and widely used alternative to native RPE. However, replication of the native RPE phenotype becomes more difficult because these cells lose their specialized phenotype after multiple passages ...
Duncan, Todd, Jaworski, Cynthia, Kutty, R Krishnan, Lakkaraju, Aparna, Poliakov, Eugenia, Postnikova, Olga A, Redmond, T Michael, Samuel, William, Tan, Li Xuan   +8 more
core   +2 more sources

Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization

Stem cell research & therapeutics, 2017
Dysfunction of the retinal pigment epithelium (RPE) is implicated in numerous forms of retinal degeneration. The readily accessible environment of the eye makes it particularly suitable for the transplantation of RPE cells, which can now be derived from ...
Roni A. Hazim, Saravanan Karumbayaram, Mei Jiang, A. Dimashkie, V. Lopes, Douran Li, B. L. Burgess, P. Vijayaraj, Jackelyn A. Alva-Ornelas, J. Zack, D. Kohn, B. Gomperts, A. Pyle, W. Lowry, David S. Williams   +14 more
semanticscholar   +1 more source

Substituent‐Based Modulation of Self‐Assembly and Immunogenicity of Amphipathic Peptides

Advanced Science, EarlyView.
This study systematically investigates how positional and subtle changes, such as substituents on the phenyl ring attached to short amphipathic peptides, influence their self‐assembly, fibril morphology, and immunogenic responses. ABSTRACT Self‐assembled peptide‐based biomaterials provide versatile platforms for biomedical uses, featuring customizable ...
Anirban Das, Ushasi Pramanik, Elise M. Brown, Chih‐Yun Liu, Huan Gong, Jonathan Fascetti, Mark Gibson, Samuel Stealey, Silviya P. Zustiak, Cory Berkland, Piyoosh Sharma, Meredith E. Jackrel, Mark A. White, Jai S. Rudra   +13 more
wiley   +1 more source

A Conservatıve Treatment Approach In A Sceletal Class III Case. A Case Report

Turkish Journal of Orthodontics, 1995
Rapid maxillary expansion (R.M.E.) has a special place in orthodontic treatments. It is based on the principle of opening of the sutura palatina media. Among indications of the R.M.E. were collaps due to maxillary deficency, nasal insufficiency and cleft
Enis Güray, Ali İhya Karaman
doaj   +1 more source

Differentiation/Purification Protocol for Retinal Pigment Epithelium from Mouse Induced Pluripotent Stem Cells as a Research Tool. [PDF]

PLoS ONE, 2016
To establish a novel protocol for differentiation of retinal pigment epithelium (RPE) with high purity from mouse induced pluripotent stem cells (iPSC).Retinal progenitor cells were differentiated from mouse iPSC, and RPE differentiation was then ...
Yuko Iwasaki, Sunao Sugita, Michiko Mandai, Shigenobu Yonemura, Akishi Onishi, Shin-Ichiro Ito, Manabu Mochizuki, Kyoko Ohno-Matsui, Masayo Takahashi   +8 more
doaj   +1 more source

Microtubule motors transport phagosomes in the RPE, and lack of KLC1 leads to AMD-like pathogenesis. [PDF]

, 2015
The degradation of phagosomes, derived from the ingestion of photoreceptor outer segment (POS) disk membranes, is a major role of the retinal pigment epithelium (RPE). Here, POS phagosomes were observed to associate with myosin-7a, and then kinesin-1, as
Diemer, Tanja, Esteve-Rudd, Julian, Jiang, Mei, Lillo, Concepción, Lopes, Vanda S, Rump, Agrani, Williams, David S   +6 more
core   +1 more source

The physiological and mechanical demands of aerobics, indoor cycling, and netball in recreationally active females [PDF]

, 2019
Background Group-based exercise is a popular method of improving fitness. However, limited research exists on the mul- tidisciplinary responses to group-based exercise. Aims The aim of this study was to compare the physiological and mechanical demands of
GREIG, MATT, MARRIN, KELLY, MCIVER, VICTORIA   +2 more
core   +2 more sources

LncRNA ZNF503-AS1 promotes RPE differentiation by downregulating ZNF503 expression

Cell Death and Disease, 2017
Long noncoding RNAs (lncRNAs) have important roles in various biological processes. Our previous work has revealed that dedifferentiation of retinal pigment epithelium (RPE) cells contributes to the pathology of age-related macular degeneration (AMD ...
Xue Chen, Chao Jiang, Bing Qin, Guohua Liu, Jiangdong Ji, Xiantao Sun, Min Xu, Sijia Ding, Meidong Zhu, Guofu Huang, B. Yan, Chen Zhao   +11 more
semanticscholar   +1 more source

Oral Celastrol Nanomedicine Targeting Intestinal Antigen‐Presenting Cells to Effectively Mitigate Autoimmune Uveitis via Gut‐Retina Axis

Advanced Science, EarlyView.
Oral nanoCEL exhibits effective intestinal targeting of antigen‐presenting cells and restores the Th17/Treg balance in lymph nodes and spleen, ultimately protecting the blood‐retinal barrier by inhibiting peripheral immune cell infiltration and suppressing retinal glial cell activation.
Jinrun Chen, Yuqin Wu, Bofei Xu, Jiabei Hou, Yijing Li, Yuhan Hu, Yutuo Zhu, Wenqiao Zhang, Shuqi Feng, Huanting Jin, Yuchen Cheng, Yuanyuan Jin, Jianhong Zhou, Xingyi Li   +13 more
wiley   +1 more source

Impact of Massage Gun on Rating of Perceived Exertion (RPE) in Soccer Players

International Journal of Disabilities Sports and Health Sciences
This study aims to determine the effect of using massage gun media on RPE (Rated Perceived Exertion) in soccer players. The method used is an experimental approach with a one-group pretest-posttest model design. The research instrument used is RPE.
Ridha Mustaqim, Dery Rimasa, Kardjono Kardjono, Mardiana Mazaulan   +3 more
doaj   +1 more source