Results 171 to 180 of about 74,456 (268)

The impact of biological sex and stroke volume constituents on heterogeneity in the Q̇$\dot{Q}$–V̇O2${{\dot{V}}_{{{{\mathrm{O}}}_2}}}$ relationship and skeletal muscle saturation during cycling

Experimental Physiology, EarlyView.
Abstract Interindividual variability in the cardiac output (Q̇$\dot{Q}$) to the rate of oxygen consumption (V̇O2${{\dot{V}}_{{{{\mathrm{O}}}_2}}}$) slope (Q̇$\dot{Q}$–V̇O2${{\dot{V}}_{{{{\mathrm{O}}}_2}}}$) in healthy males is related to stroke volume (SV); however, the impact of differences in left ventricular (LV) structure and function as well as ...
Adam N. Di Salvo, Sinan Osman, Jacob L. Schwartz, Nino Nikolovski, Robert F. Bentley   +4 more
wiley   +1 more source

Paired DNA and RNA sequencing uncovers common and rare variation regulating human retinal gene expression. [PDF]

Nat Commun
Sampson J, Segrè AV, Bujakowska KM, Clark SJ, Bishop PN, Haynes S, Baralle D, Al-Deek J, Holden S, Anderson B, Hayes A, Kemal RA, Thomas HB, O'Keefe RT, Banka S, Black GC, Sergouniotis PI, Ellingford JM.   +17 more
europepmc   +1 more source

Editorial: Vigour, vitiligo and the RPE

Pigment Cell Research, 2006
openaire   +2 more sources

Comparison of exercise training and repeated hot water immersion on vascular function in overweight older adults

Experimental Physiology, EarlyView.
Abstract Recent studies suggest that heat exposure may benefit cardiovascular health, but in overweight and obese older adults, the chronic effects of heat therapy on artery function are still uncertain. We aimed to compare the effects of 12 weeks (3×/week, 40 min) of aerobic exercise (EXE) to hot water immersion (HWI) and an inactive control group ...
Juliene G. Costa, Joao Carlos Locatelli, Kristanti W. Wigati, Louise H. Naylor, Helen Jones, Andrew Haynes, Daniel J. Green   +6 more
wiley   +1 more source

Pulmonary arterial mechanoreceptors modulate exercise‐induced sympathetic activation in healthy humans during moderate‐intensity hypoxic exercise

The Journal of Physiology, EarlyView.
Abstract figure legend This randomized cross‐over trial (N = 12) addressed the hypothesis that selective reduction of pulmonary arterial pressure (i.e. manipulation of pulmonary arterial mechanoreceptor activation) during hypoxic exercise would reduce sympathetic outflow (muscle sympathetic nerve activity (MSNA)) in healthy humans.
Michiel T. Ewalts, Thomas D. Griffiths, Andrew J. M. Douglas, Elliott J. Jenkins, Guto Wyn Hughes, Craig D. Steinback, Lydia L. Simpson, Samuel J. Oliver, Mike Stembridge, Jonathan P. Moore   +9 more
wiley   +1 more source

Retinal Pigment Epithelium Ageing: Cellular and Molecular Mechanisms of Long-Term Homeostasis and Age-Related Dysfunction. [PDF]

Cells
Yang Y, Liu P, Li J, Deng Y, Xiao L, Peng Q, Peng J.   +6 more
europepmc   +1 more source

Arterial–venous differences of brain‐derived neurotrophic factor isoforms across the brain and muscle after exercise at different intensities

The Journal of Physiology, EarlyView.
Abstract figure legend Exercise‐induced increases in forearm venous plasma and serum brain‐derived neurotrophic factor (BDNF) are often assumed to be indicative of release from the brain. Sixteen healthy and physically fit adults (20–40 years old) were recruited to investigate whether exercise‐induced changes in forearm venous mature BDNF (mBDNF) and ...
Olga Tarassova, Yiwen Jiang, Helena Wallin, Mats Jensen‐Urstad, Nikola Drca, Julia Röja, Marjan Pontén, Abram Katz, Jonna Nilsson, Maria M. Ekblom, Marcus Moberg   +10 more
wiley   +1 more source

Single-cell and spatial analyses reveal endothelial-macrophage inflammatory crosstalk in dry age-related macular degeneration. [PDF]

J Transl Med
Chen Y, Liu C, Chen J, Huang Y, Pan G, Wang P, Hu Y, Chen L, Zhang Y, Wang Y.   +9 more
europepmc   +1 more source

Determinants of maximal oxygen uptake in highly trained females and males: a mechanistic study of sex differences using advanced invasive methods

The Journal of Physiology, EarlyView.
Abstract figure legend The results from this study show that maximal cardiac output, stroke volume and leg blood flow are similar between highly trained females and males after normalisation to lean body mass (LBM). However, the 10% higher haemoglobin concentration ([Hb]) and arterial O2 content in males result in higher systemic and leg O2 delivery ...
Øyvind Skattebo, Marcos Martin‐Rincon, Bjarne Rud, Joachim Nielsen, Lars Henrik N. Hegg, Andreas V. Kleive, Niels Ørtenblad, Øyvind Sandbakk, Robert Boushel, Hans‐Christer Holmberg, Jose A.L. Calbet, Jostein Hallén   +11 more
wiley   +1 more source