Results 181 to 190 of about 74,456 (268)

Independent Degeneration of Photoreceptors and Retinal Pigment Epithelium: Multimodal Imaging Evidence From Choroideremia Carriers. [PDF]

Invest Ophthalmol Vis Sci
Han X, Yu Y, Wei X, Sun Z, Li H, Zou X, Sui R.   +6 more
europepmc   +1 more source

Sex‐specific metabolic responses to glucagon receptor agonism and modulation of the FGF21‐glucagon axis in female mice

The Journal of Physiology, EarlyView.
Abstract figure legend Therapies targeting the glucagon receptor are being explored for obesity treatment, yet most preclinical studies remain male biased. In this study, Merrild and Johansen et al. show that in diet‐induced obese wild‐type mice a long‐acting glucagon analogue (LA‐Gcg) elicits sexually dimorphic effects on weight loss, food intake ...
Christoffer Merrild, Valdemar Brimnes Ingemann Johansen, Christoffer Clemmensen, Pablo Ranea‐Robles   +3 more
wiley   +1 more source

Dissecting the interplay of model-based control, impulsivity and compulsivity on self-control in daily life. [PDF]

Sci Rep
Dück K, Overmeyer R, Wüllhorst R, Endrass T.   +3 more
europepmc   +1 more source

Glucose and fructose contributions to exogenous carbohydrate oxidation and performance at moderate altitude

The Journal of Physiology, EarlyView.
Abstract figure legend Co‐ingesting fructose with glucose increases exogenous carbohydrate oxidation at sea level, but its effect at altitude is unclear. This study compared glucose–fructose (GLU–FRU), glucose alone (GLU) and placebo during 120 min of running at 70% V̇O2max${{\dot{V}}_{{{{\mathrm{O}}}_2}{\mathrm{max}}}}$ at 2500 m in eight males.
Nicola C. Arjomandkhah, Andy J. King, Alex Griffiths, Roderick F. G. J. King, Douglas, J. Morrison, Thomas Preston, John P. O'Hara   +7 more
wiley   +1 more source

Post‐exercise ketone supplementation improves endurance performance and mitochondrial adaptations during an 8‐week endurance training intervention

The Journal of Physiology, EarlyView.
Abstract figure legend Twenty‐eight trained males completed 8 weeks of supervised indoor cycling training, receiving post‐exercise and pre‐sleep ketone monoester (KE, n = 14) or isocaloric placebo (CON, n = 14). Both groups improved 30 min time‐trial performance with training, but KE achieved a 4% higher power output than CON at the end of the training
Ruben Robberechts, Youri Bekhuis, Myrthe Stalmans, Wout Lauriks, Martijn Kusters, Karim Taha, Thomas Rosseel, Guido Claessen, Chiel Poffé   +8 more
wiley   +1 more source

IND-enabling safety and efficacy of RPESC-RPE-4W, an adult RPE progenitor cell therapy for dry age-related macular degeneration. [PDF]

Cell Rep Med
Arduini BL, Blenkinsop TA, Naimark M, Borden S, Charniga C, Campbell M, Rugenstein N, Davis RJ, Alam N, Prusky G, Frye AM, Mazzoni F, Finnemann SC, Zhao C, Lederman P, Saini JS, Kiehl TR, Renga N, Kozak JA, Rocchio PA, Salero E, Boles NC, Goderie SK, Lotz S, Adamo JE, Zaccaglino S, Onanuga K, Fiske M, Capela A, Temple S, Stern JH.   +30 more
europepmc   +1 more source

Müller Glia–Vasculature Interactions in the Developing Retina

Glia, Volume 74, Issue 10, October 2026.
Retinal vascular layers form normally despite loss of cholinergic retinal waves. Müller glial processes contact endothelial tip cells early and form Aquaporin‐4‐enriched endfeet. Glial endfoot calcium signals are compartmentalized and occur largely independently of neural activity. ABSTRACT Coordinated signaling among neurons, glia, and the vasculature
Samira Monshietehadi, Angel J. Garcia, Benjamin E. Smith, Matthew Tarchick, Kiara Abhayaratne, Aileen Conley, Marla B. Feller   +6 more
wiley   +1 more source

Patient induced pluripotent stem cells identify specificities of a reticular pseudodrusen phenotype in age-related macular degeneration. [PDF]

Genome Med
Hall JC, Krishna Sudhakar K, Daniszewski M, Senabouth A, Abbott CJ, Liang HH, Kumar H, Lidgerwood GE, Mirzaei M, Ma JY, Atkeson T, Hirokawa Y, Nandrot EF, Barnett A, Cazevieille C, Manes G, Mountford S, Thompson P, Fletcher EL, Wu Z, Bahlo M, Ansell BRE, Paull D, Hewitt AW, Guymer RH, Powell JE, Pébay A.   +26 more
europepmc   +1 more source