The Intersection of Serine Metabolism and Cellular Dysfunction in Retinal Degeneration
In the past, the importance of serine to pathologic or physiologic anomalies was inadequately addressed. Omics research has significantly advanced in the last two decades, and metabolomic data of various tissues has finally brought serine metabolism to ...
Tirthankar Sinha +3 more
doaj +1 more source
Development-related mitochondrial properties of retinal pigment epithelium cells derived from hEROs [PDF]
AIM: To explore the temporal mitochondrial characteristics of retinal pigment epithelium (RPE) cells obtained from human embryonic stem cells (hESC)-derived retinal organoids (hEROs-RPE), to verify the optimal period for using hEROs-RPE as donor cells ...
Hao-Jue Xu +3 more
doaj +1 more source
Deletion of TSPO resulted in change of metabolomic profile in retinal pigment epithelial cells [PDF]
Age-related macular degeneration is the main cause of vision loss in the aged population worldwide. Drusen, extracellular lesions formed underneath the retinal pigment epithelial (RPE) cells, are a clinical feature of AMD and associated with AMD ...
Abdulwahab Alamri +7 more
core +2 more sources
The sustainable delivery of sexual violence prevention education in schools [PDF]
Sexual violence is a crime that cannot be ignored: it causes our communities significant consequences including heavy economic costs, and evidence of its effects can be seen in our criminal justice system, public health system, Accident Compensation ...
Good, G, Julich, SJ, Oak, E, Terrell, J
core +4 more sources
POWER AND INFORMATION SYSTEM OF LINEAR COMPLEX OF SWITCHING DEVICES
Power lines icing can cause serious accidents up to fall of poles and wire break. An effective way , get rid of ice on wires is its fusion of electric shock.
Andrey Koltsov +7 more
doaj
Autophagy in the eye: from physiology to pathophysiology
Autophagy is a catabolic self-degradative pathway that promotes the degradation and recycling of intracellular material through the lysosomal compartment. Although first believed to function in conditions of nutritional stress, autophagy is emerging as a
Paloma B. Liton +15 more
doaj +1 more source
The effect of acute caffeine ingestion on upper and lower body anaerobic exercise performance [PDF]
The current study examined the effect of acute caffeine ingestion on mean and peak power production, fatigue index and rating of perceived exertion (RPE) during upper body and lower body Wingate anaerobic test (WANT) performance.
Andre T. +9 more
core +1 more source
Reward prediction error and declarative memory [PDF]
Learning based on reward prediction error (RPE) was originally proposed in the context of nondeclarative memory. We postulate that RPE may support declarative memory as well.
De Loof, Esther +2 more
core +1 more source
Geographic atrophy of the macula
Geographic atrophy of the macula is a late form of dry AMD. Changes found on optical coherence tomography imaging (OCT) include Retinal Pigment Epithelium (RPE) atrophic changes and window defects, with a pronounced photorecetor layer damage.
Alaa M Fadel
doaj +1 more source
When the outcome is different than expected : subjective expectancy shapes reward prediction error at the FRN level [PDF]
Converging evidence in human electrophysiology suggests that evaluative feedback provided during performance monitoring (PM) elicits two distinctive and successive ERP components: the feedback-related negativity (FRN) and the P3b.
Moors, Agnes +3 more
core +1 more source

