Results 1 to 10 of about 84,753 (164)
Guggul- a herbal panacea from India [PDF]
Farmacja Polska, 2020Guggul is an oleo-gum resin obtained from plants belonging to the genera Commiphora and Boswellia, within the Burseraceae family. Its source are mainly two species: Commiphora wightii (Arn.) Bhand. (syn. Commiphora mukul (Hook. ex Stocks) Engl.
Marta Anna Wojciechowska+2 more
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Impact of legal regulations on the level of competitiveness of community pharmacies [PDF]
Farmacja Polska, 2020In recent years, a significant increase in intra-sector competition has been observed in the community pharmacy market. This phenomenon has been intensified by the increase in the concentration of owners and the emergence of so-called pharmacy chains. It
Urszula Religioni, Teresa Pakulska
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AAV2/4-RS1 gene therapy in the retinoschisin knockout mouse model of X-linked retinoschisis
PLoS ONE, 2022Objective To evaluate efficacy of a novel adeno-associated virus (AAV) vector, AAV2/4-RS1, for retinal rescue in the retinoschisin knockout (Rs1-KO) mouse model of X-linked retinoschisis (XLRS).
Brittni A Scruggs+8 more
semanticscholar +1 more source
Investigative Ophthalmology and Visual Science, 2022
Purpose Loss of retinoschisin (RS1) function underlies X-linked retinoschisis (XLRS) pathology. In the retina, both photoreceptor inner segments and bipolar cells express RS1. However, the loss of RS1 function causes schisis primarily in the inner retina.
C. Vijayasarathy+7 more
semanticscholar +1 more source
Purpose Loss of retinoschisin (RS1) function underlies X-linked retinoschisis (XLRS) pathology. In the retina, both photoreceptor inner segments and bipolar cells express RS1. However, the loss of RS1 function causes schisis primarily in the inner retina.
C. Vijayasarathy+7 more
semanticscholar +1 more source
THE ROLE OF VITAMIN D IN NEOPLASMS AND NEURODEGENERATION DISEASES - A REVIEW OF THE LITERATURE [PDF]
Farmacja Polska, 2020In recent years, a significant increase in the incidence of cancer and neurodegenerative diseases has been observed. This is mainly because of the higher life expectancy and thus prolonged contact with risk factors, inadequate diet and lack of physical ...
Magdalena Waszyk-Nowaczyk+1 more
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XLRS Rat with Rs1-/Y Exon-1-Del Shows Failure of Early Postnatal Outer Retina Development
Genes, 2022We generated a Long Evans transgenic rat with targeted deletion of the whole Rs1 exon-1 and evaluated the pathological retinal phenotype of this Rs1-/Y rat model of X-linked retinoschisis (XLRS).
Eun-Ah Ye+5 more
semanticscholar +1 more source
Magnetic Fields Reduce Apoptosis by Suppressing Phase Separation of Tau-441
Research, 2023The biological effects of magnetic fields (MFs) have been a controversial issue. Fortunately, in recent years, there has been increasing evidence that MFs do affect biological systems. However, the physical mechanism remains unclear.
Wenzhang Lin+6 more
semanticscholar +1 more source
Hydrogels - compounded dermatological preparations [PDF]
Farmacja Polska, 2020Hydrogels are a physicochemical system in which an aqueous phase is gelled with a certain gelling polymer. They can make a good alternative to conventional lipophilic or absorption ointment bases, especially if the medicine should be administered to ...
Bianka Jacyna+2 more
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Human Gene Therapy, 2020
To understand RS1 gene interaction networks in the X-linked retinoschisis (XLRS) mouse retina (Rs1−/y), we analyzed the transcriptome by RNA sequencing before and after in vivo expression of exogenous retinoschisin (RS1) gene delivered by AAV8.
C. Vijayasarathy+4 more
semanticscholar +1 more source
To understand RS1 gene interaction networks in the X-linked retinoschisis (XLRS) mouse retina (Rs1−/y), we analyzed the transcriptome by RNA sequencing before and after in vivo expression of exogenous retinoschisin (RS1) gene delivered by AAV8.
C. Vijayasarathy+4 more
semanticscholar +1 more source
Indonesian Journal of Pharmacy, 2013
Cytochrome P450 3A4 (CYP3A4) is a phase 1 metabolism enzyme which is responsible for the metabolism of about 3040% drug in the market. This CYP3A4 is the most abundant CYP450 expressed in human body and also the one who is responsible for the ...
Dewi Setyaningsih+3 more
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Cytochrome P450 3A4 (CYP3A4) is a phase 1 metabolism enzyme which is responsible for the metabolism of about 3040% drug in the market. This CYP3A4 is the most abundant CYP450 expressed in human body and also the one who is responsible for the ...
Dewi Setyaningsih+3 more
doaj +1 more source