Results 91 to 100 of about 15,770 (195)

A Synthetic Transcriptional Activator of Genes Associated with the Retina in Human Dermal Fibroblasts. [PDF]

, 2015
Small molecules capable of modulating epigenetic signatures can activate the transcription of tissue-restricted genes in a totally unrelated cell type and have potential use in epigenetic therapy.
Bando, Toshikazu, Chandran, Anandhakumar, Hashiya, Kaori, Kashiwazaki, Gengo, Pandian, Ganesh N, Sato, Shinsuke, Sugiyama, Hiroshi, Syed, Junetha, Taniguchi, Junichi   +8 more
core   +1 more source

Molecular characterization of transformer, transformer‐2, and doublesex genes in the carambola fruit fly, Bactrocera carambolae, revealing potential for genetic pest management

Insect Science, Volume 33, Issue 2, Page 566-585, April 2026.
Abstract Globalization and climate change may be driving the spread of the quarantine fruit fly, Bactrocera carambolae, highlighting the need for ecofriendly control methods like the Sterile Insect Technique (SIT), which relies on releasing sterile males to reduce wild populations.
Kamoltip Laohakieat, Thanalai Poonsiri, Nidchaya Aketarawong   +2 more
wiley   +1 more source

Generation of induced pluripotent stem cell (iPSC) line ZOCi003-A derived from peripheral blood mononuclear cells of X-linked juvenile retinoschisis harboring a hemizygous mutation in RS1 gene

Stem Cell Research, 2021
X-linked juvenile retinoschisis (XLRS) is an inherited disease characterized by splitting within inner retinal layers and impaired vision, which begins in childhood and occurs mostly in males. Peripheral blood mononuclear cells (PBMCs) were isolated from
Yafen Liu, Xinyu Liu, Mingwei Huang, Linyan Zhang, Jinglin Lu, Zhaotian Zhang, Xiaoyan Ding   +6 more
doaj   +1 more source

Radial Spokes-A Snapshot of the Motility Regulation, Assembly, and Evolution of Cilia and Flagella [PDF]

, 2016
Propulsive forces generated by cilia and flagella are used in events that are critical for the thriving of diverse eukaryotic organisms in their environments. Despite distinctive strokes and regulations, the majority of them adopt the 9+2 axoneme that is
Liu, Yi, Yang, Pinfen, Zhu, Xiaoyan
core   +1 more source

Peripheral fundus findings in X-linked retinoschisis [PDF]

, 2017
BACKGROUND/AIMS: Vitreous haemorrhage (VH) and retinal detachment (RD) cause a precipitous decline in vision in a subset of patients with X-linked retinoschisis (XLRS), an otherwise a slowly progressive condition.
Ali, N, Blachley, T, Fahim, AT, Michaelides, M   +3 more
core   +1 more source

Identification of evolutionarily conserved exons as regulated targets for the splicing activator Tra2β in development [PDF]

, 2011
Alternative splicing amplifies the information content of the genome, creating multiple mRNA isoforms from single genes. The evolutionarily conserved splicing activator Tra2β (Sfrs10) is essential for mouse embryogenesis and implicated in spermatogenesis.
Best, A., Bourgeois, C. F., Curk, T., Dalgliesh, C., Ehrmann, I., Elliott, D. J., Grellscheid, D., Grellscheid, S., Jackson, M. S., Jakubik, M., Liu, Y., Mende, Y., Rossbach, K., Storbeck, M., Stévenin, J., Wirth, B.   +15 more
core   +8 more sources

Isolation and Mapping of Human Homologues of an Imprinted Mouse GeneU2af1-rs1

Genomics, 1995
We have isolated human homologues of the imprinted mouse gene, U2af1-rs1. Two different types of cDNAs and three distinct genomic DNAs belonging to different groups were isolated. We have identified chromosomal genes corresponding to each cDNA by restriction mapping and sequencing.
Kazunori Kitagawa, Xudong Wang, Izuho Hatada, Tetsuji Yamaoka, Hiroshi Nojima, Johji Inazawa, Tatsuo Abe, Kohzoh Mitsuya, Mitsuo Oshimura, Atsuo Murata, Morito Monden, Tsunehiro Mukai   +11 more
openaire   +2 more sources

Epigenetic regulation of the imprinted U2af1‐rs1 gene during retinoic acid‐induced differentiation of embryonic stem cells [PDF]

Development, Growth & Differentiation, 2006
Epigenetic modifications such as DNA methylation and changes in chromatin structure are changes in the chemical composition or structure of DNA that work by regulating gene expression. Their mechanisms of action have been generally studied in imprinted genes.
Noelia, Andollo, María D, Boyano, Ricardo, Andrade, Juan M, Aréchaga   +3 more
openaire   +2 more sources

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, Volume 4, Issue 1, March 2026.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

Genome sequence of canine herpesvirus [PDF]

, 2016
Canine herpesvirus is a widespread alphaherpesvirus that causes a fatal haemorrhagic disease of neonatal puppies. We have used high-throughput methods to determine the genome sequences of three viral strains (0194, V777 and V1154) isolated in the United ...
Davison, Andrew, Graham, Elizabeth M., McDonald, Michael, Papageorgiou, Konstantinos V., Suárez, Nicolás M., Wilkie, Gavin S.   +5 more
core   +2 more sources