Results 41 to 50 of about 164,355 (372)

Respiratory syncytial virus: Clinical and epidemiological pattern in pediatric patients admitted to a children’s hospital between 2000 and 2013 [PDF]

, 2014
INTRODUCTION: Respiratory syncytial virus (RSV) is the major causative organism associated with acute lower respiratory tract infections in children.The objective of this study was to describe the clinical and epidemiological pattern of RSV and identify ...
Bakir, Julia, Castellano, Verónica, Gentile, Ángela, Grobaporto, Marcela, Juárez, María del Valle, Lucion, María Florencia, Mistchenko, Alicia Susana, Romanin, Viviana Sandra, Viegas, Mariana   +8 more
core   +1 more source

Estimated incidence of respiratory hospitalizations attributable to RSV infections across age and socioeconomic groups

Pneumonia, 2022
Background Surveillance for respiratory syncytial virus (RSV) likely captures just a fraction of the burden of disease. Understanding the burden of hospitalizations and disparities between populations can help to inform upcoming RSV vaccine programs and ...
Zhe Zheng, J. Warren, E. Shapiro, V. Pitzer, D. Weinberger   +4 more
semanticscholar   +1 more source

Prevention of bronchiolitis from the hospital to home: enviromental and pharmacological strategies

Journal of Pediatric and Neonatal Individualized Medicine, 2015
Bronchiolitis is one of the major cause of mortality and morbidity during infancy, with high hospitalization rate during epidemic season for high risk infants during the first year of life.
Andrea Dotta
doaj   +1 more source

Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state [PDF]

, 2017
Human respiratory syncytial virus (RSV) is the main cause of lower respiratory tract infections in young children. The RSV fusion protein (F) is highly conserved and is the only viral membrane protein that is essential for infection.
Chen, Man, Gilman, Morgan SA, Graham, Barney S, Kabeche, Stephanie C, Kanekiyo, Masaru, Mas, Vicente, McLellan, Jason S, Melero, José A, Rossey, Iebe, Saelens, Xavier, Schepens, Bert, Sedeyn, Koen, Spitaels, Jan, Wrapp, Daniel   +13 more
core   +2 more sources

International changes in respiratory syncytial virus (RSV) epidemiology during the COVID‐19 pandemic: Association with school closures

Influenza and Other Respiratory Viruses, 2022
Little RSV activity was observed during the first expected RSV season since the COVID‐19 pandemic. Multiple countries later experienced out‐of‐season RSV resurgences, yet their association with non‐pharmaceutical interventions (NPIs) is unclear.
Marie-Noëlle Billard, P. M. van de Ven, Bianca Baraldi, L. Kragten-Tabatabaie, L. Bont, J. Wildenbeest   +5 more
semanticscholar   +1 more source

Expected Impact of Universal Immunization With Nirsevimab Against RSV-Related Outcomes and Costs Among All US Infants in Their First RSV Season: A Static Model

Journal of Infectious Diseases, 2022
Background Respiratory syncytial virus (RSV) is associated with substantial morbidity in the United States, especially among infants. Nirsevimab, an investigational long-acting monoclonal antibody, was evaluated as an immunoprophylactic strategy for ...
A. Kieffer, Matthieu Beuvelet, A. Sardesai, Robert Musci, S. Milev, J. Roiz, Jason K H Lee   +6 more
semanticscholar   +1 more source

Passive and active immunization against respiratory syncytial virus for the young and old

Expert Review of Vaccines, 2017
Introduction: Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infections in infants worldwide and also causes significant disease in the elderly.
Tonya Villafana, Judith Falloon, M. Pamela Griffin, Qing Zhu, Mark T. Esser   +4 more
doaj   +1 more source

Non-Coding RNAs and Their Role in Respiratory Syncytial Virus (RSV) and Human Metapneumovirus (hMPV) Infections

Viruses, 2020
Recent high-throughput sequencing revealed that only 2% of the transcribed human genome codes for proteins, while the majority of transcriptional products are non-coding RNAs (ncRNAs).
Wenzhe Wu, Eun-Jin Choi, Inhan Lee, Yong Sun Lee, Xiaoyong Bao   +4 more
doaj   +1 more source

Strategies to develop vaccines of pediatric interest

Expert Review of Vaccines, 2017
Introduction: The success of the vaccines available on the market has significantly increased interest in vaccine development. Areas covered: The main aim of this paper is to discuss the most important vaccines of pediatric interest that are currently ...
Susanna Esposito, Nicola Principi
doaj   +1 more source

Roadblocks to translational challenges on viral pathogenesis. [PDF]

, 2013
Distinct roadblocks prevent translating basic findings in viral pathogenesis into therapies and implementing potential solutions in the clinic. An ongoing partnership between the Volkswagen Foundation and Nature Medicine resulted in an interactive ...
Deeks, Steven, Drosten, Christian, Picker, Louis, Subbarao, Kanta, Suzich, Joann   +4 more
core   +1 more source