Results 131 to 140 of about 565,475 (306)

RT-LAMP primers for detection of WSSMV.

open access: yes
To accurately determine the spread of any pathogen, including plant viruses, a quick, sensitive, cost-effective, point-of-care diagnostic assay is necessary.
Paolo Mussano (18078500)   +8 more
core   +1 more source

CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome

open access: yesAdvanced Science, EarlyView.
By modeling Lowe syndrome using patient‐derived iPSCs, this study establishes a human disease model that faithfully recapitulates OCRL deficiency‐associated ciliary and cytoskeletal defects. The model enables evaluation of both mutation‐agnostic DNA augmentation and CRISPR‐mediated mutation correction strategies, both of which restore OCRL function and
Siyu Chen   +11 more
wiley   +1 more source

Yoda1‐Functionalized Nanozymes Coordinate Piezo1 Activation and Mitochondrial Protection to Reprogram the Diabetic Osteoimmune Micromilieu and Promote Vascularized Bone Repair

open access: yesAdvanced Science, EarlyView.
Diabetic bone defects remain a critical clinical challenge. A 3D‐printed BCPG‐MF@Y scaffold, embedding Yoda1‐functionalized manganese dioxide‐ferritin nanozymes, scavenges mtROS, suppresses the cGAS–STING pathway, and reverses cellular senescence, while Yoda1 activates Piezo1 to direct BMSCs fate to synergistically reprogram the osteoimmune ...
Qing‐Song Deng   +16 more
wiley   +1 more source

Rapid, sensitive and effective diagnostic tools for foot-and-mouth disease virus in Africa

open access: yesOnderstepoort Journal of Veterinary Research, 2014
Speed is paramount in the diagnosis of highly infectious diseases, such as foot-and-mouth disease (FMD), as well as for emerging diseases; however, simplicity is required if a test is to be deployed in the field.
Christopher J. Kasanga   +11 more
doaj   +1 more source

Comparative limit of detection between Svanova LFD, RT-qPCR, RT-LAMP-LFD and the RT-LAMP assays.

open access: yes, 2014
10 fold dilutions of FMDV containing epithelial suspensions were analysed using the Svanova LFD device (a) by applying the suspensions directly to the device.
Donald P. King (116717)   +6 more
core   +1 more source

Primer sequences used for RT-LAMP targeting DENV serotypes.

open access: yes, 2022
Primer sequences used for RT-LAMP targeting DENV serotypes.
Yutaka Suzuki (1379)   +6 more
core   +1 more source

A ROS‐Responsive and Mucoadhesive Thermosensitive Hydrogel Encapsulated with Mizoribine for Synergistic Dry Eye Therapy

open access: yesAdvanced Science, EarlyView.
The ROS‐responsive in situ thermosensitive MZR@SPPP hydrogel system enables dual‐stage drug loading and sustained ocular delivery. Upon administration, it gelates at ocular surface temperature, enhancing ocular adhesion. By scavenging free radicals, restoring NRF2‐mediated antioxidant defense and mitochondrial homeostasis, and suppressing inflammatory ...
Danyi Qin   +13 more
wiley   +1 more source

Performance of RT-LAMP, RT-PCR and RDT in comparison with thick smear microscopy.

open access: yes, 2016
Performance of RT-LAMP, RT-PCR and RDT in comparison with thick smear microscopy.
Dylan Guelig (666473)   +13 more
core   +1 more source

Ultrafast Micrometric Laser Structuring of Polymer Surfaces for Highly Organized Skeletal Muscle Tissue Modeling

open access: yesAdvanced Science, EarlyView.
Standard cell culture supports were functionalized by laser‐structuring to generate advanced topographies tailored to skeletal muscle tissue. The physicochemical modifications of the polymeric surfaces and their interactions with cells were thoroughly investigated, confirming both safety and effectiveness in guiding muscle cell organization.
Lucas Duvert   +10 more
wiley   +1 more source

Low Threshold Vertical Cavity Surface Emitting Lasers Based on CsPbI3 Thin Films

open access: yesAdvanced Science, EarlyView.
The first vertical‐cavity surface‐emitting laser (VCSEL) based on CsPbI3 thin films is fabricated by planar hot pressing. By optimizing the cavity design through optical gain assessment and rigorous coupled‐wave analysis, the VCSEL achieved an exceptionally low lasing threshold of 2.8 µJ cm−2.
Naho Kurahashi   +11 more
wiley   +1 more source

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