Results 201 to 210 of about 2,220,062 (335)

Bioengineered Pancreatic Cancer Immunosuppressive Microenvironment Models for Screening Immunotherapies

Advanced Healthcare Materials, EarlyView.
Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro, Margarida Henriques‐Pereira, Bruno M. Neves, Vítor M. Gaspar, João F. Mano   +4 more
wiley   +1 more source

Development of a multiplex and universal RT-PCR assay for hemagglutinin and neuraminidase subtyping of avian influenza virus. [PDF]

J Vet Sci
An SH, Heo GB, Kang YM, Lee YJ, Lee KN.
europepmc   +1 more source

A Heparin‐Functionalized Scaffold with HB‐EGF Immobilization for Tissue Engineering

Advanced Healthcare Materials, EarlyView.
In this study, a heparin‐functionalized scaffold is designed for bio‐mimicking growth factors reservoir function of extracellular matrix. Due to the presence of heparin‐binding domain, heparin‐binding epidermal growth factor‐like growth factor (HB‐EGF) is effectively and spatially captured by heparin‐functionalized scaffold.
Bowu Peng, Huajian Chen, Chengyu Lu, Tianjiao Zeng, Man Wang, Toru Yoshitomi, Naoki Kawazoe, Yingnan Yang, Guoping Chen   +8 more
wiley   +1 more source

Engineering a Thermostable Reverse Transcriptase for RT-PCR Through Rational Design of <i>Pyrococcus furiosus</i> DNA Polymerase. [PDF]

Biomolecules
Kuznetsova AA, Grishina IA, Mikushina ES, Kuznetsov NA.   +3 more
europepmc   +1 more source

Geometry‐Guided Osteogenesis in Bone‐on‐a‐Chip Systems Using Triply Periodic Minimal Surface Scaffolds

Advanced Healthcare Materials, EarlyView.
This study presents a bone‐on‐a‐chip platform incorporating TPMS scaffolds to study geometry‐dependent osteogenesis under dynamic flow. By tuning pore shape and solidity, it precisely controls mechanical cues, revealing how topological features and shear stress affect osteogenic differentiation and matrix formation.
Donggyu Kim, Giheon Ha, Minseok Kim, Minjin Kwak, Han‐Jun Kim, Junmin Lee   +5 more
wiley   +1 more source

<i>NEAT</i> and tidy: a novel RT-PCR method for the independent quantification of the <i>NEAT1_1</i> isoform. [PDF]

Biol Methods Protoc
Smith NE, Petersen J, Michael MZ.
europepmc   +1 more source

Diagnostic and Analytical Performance of a RT-PCR Test For the Detection of PRRS Virus in Serum

, 1998
Elizabeth A. Wagstrom, Kyung Joong Yoon, J.J. Zimmerman   +2 more
openalex   +1 more source

Sensitive and Specific qPCR and Nested RT-PCR Assays for the Detection of Tobacco Streak Virus in Soybean

, 2021
Cristina Zambrana-Echevarría, Mitchell G. Roth, Ranjit Dasgupta, Thomas L. German, Carol L. Groves, Damon L. Smith   +5 more
openalex   +1 more source

Metronidazole‐Loaded Cyclodextrin Nanogels for Antibacterial Therapy and Microbiota Regulation in Periodontitis

Advanced Healthcare Materials, EarlyView.
A methacrylamide β‐cyclodextrin‐based nanogel (MACD nGel) is developed to load the antimicrobial drug Metronidazole (MNZ) for topical delivery for the treatment of periodontitis. It is demonstrated that cyclodextrin nanogel (nGel) loaded with metronidazole provides an efficient drug delivery route but also has potential clinical applications and offers
Yanjing Ji, Ruichen Zhang, Dongyi Xu, Patrick C. A. van der Wel, Alessia Lasorsa, Guotai Li, Fangze Guo, Qihui Zhou, Patrick van Rijn   +8 more
wiley   +1 more source

The added diagnostic value of RT-PCR on faeces for the diagnosis of COVID-19. [PDF]

PLoS One
Van der Moeren N, van den Biggelaar R, Gast KB, Verweij JJ, Bergmans BJM, Stohr JJJM, Murk JL.   +6 more
europepmc   +1 more source