Results 201 to 210 of about 1,917,084 (305)

Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao, Rulan Ma, Zejing Lin, Huiying Zhao, Yuexian Liu, Yonghe Su, Xu Zhang, Xingyong Chen   +7 more
wiley   +1 more source

New Approach to mRNA Quantification: Additive RT-PCR

BioTechniques, 1996
A. Reyes-Engel, J. García-Villanova, J.L. Dieguez-Lucena, N. Fernández-Arcás, M. Ruiz-Galdón   +4 more
doaj   +1 more source

Genotypic distribution and molecular epidemiology of HPV in women in the UAE using PNA-based RT PCR. [PDF]

PLoS One
Finney D, Hashim ALO, Bylappa SK, Mugar AE, Nandhagopal M, Jabbar MA, Rahamathullah N.   +6 more
europepmc   +1 more source

Mitochondrial SLC25A46 Rewires Fatty Acid Oxidation to Promote Cell Proliferation and Ferroptosis Evasion in Ovarian Cancer by Stabilizing CACT

Advanced Science, EarlyView.
Mitochondrial SLC25A46 is upregulated in ovarian cancer (OC) and correlates with poor prognosis. SLC25A46 stabilizes CACT to activate fatty acid oxidation, increasing ATP and NADPH production to drive cell proliferation and ferroptosis evasion. SLC25A46 silencing sensitizes OC cells to ferroptosis and carboplatin, offering a promising therapeutic ...
Yunge Gao, Jiatao Hao, Xiaohong Zhang, Meiting Long, Yujing Feng, Xiaoyue Liu, Xuejian Li, Shujuan Liu, Xin Guo, Xiaohui Lv   +9 more
wiley   +1 more source

Quantitative RT-PCR for Human Fas (CD95) Expression

BioTechniques, 1997
Debashis Mitra, Jeffrey Laurence
doaj   +1 more source

RNAi in the Rhizarian Phytopathogen Plasmodiophora brassicae: The Causal Agent of Clubroot Disease in Cruciferous Crops

Advanced Science, EarlyView.
This study uncovers an unusual RNAi pathway in the rhizarian pathogen Plasmodiophora brassicae. In the absence of Dicer, a Drosha‐like RNase III protein supports the biogenesis of predominant 21‐nt small RNAs, and two Argonaute proteins mediate small RNA‐guided silencing.
Xiong Zhang, Yupo Wu, Jiachang Hou, Lixia Gao, Longqi Pan, Cuicui Shen, Chuanji Zhao, Feng Gao, Yi Zhang, Li Ren, Xiaoping Fang, Xiaoling Dun, Shengyi Liu, Lijiang Liu   +13 more
wiley   +1 more source

In Situ RT-PCR Using Fluorescence-Labeled Primers

BioTechniques, 1997
Ulrike Stein, Wolfgang Walther, Jana Wendt, Thomas A. Schild   +3 more
doaj   +1 more source

Development and evaluation of a real-time RT-PCR assay for Mammarenavirus guanaritoense virus detection. [PDF]

BMC Infect Dis
Dolgova AS, Gladkikh AS, Polev DE, D'Angelo P, Alarcón V, García N, Arias Y, Monsalve I, Rodriguez L, Shabalina AV, Chayeb VA, Sukhikh IS, Briceño E, Dedkov VG.   +13 more
europepmc   +1 more source

Molecular Editing Reveals a Bilobalide Chemotype that Attenuates Prolyl Endopeptidase (PREP)‐Linked Neuroinflammation

Advanced Science, EarlyView.
Molecular editing of bilobalide uncovers BB56, a PREP‐engaging chemotype with enhanced anti‐inflammatory activity in microglia. Integrated CETSA‐MS, SAR, and pathway analyses link BB56 to attenuation of p38 MAPK/NF‐κB and NLRP3‐associated inflammatory signaling, highlighting bilobalide editing as a strategy for developing neuroinflammation‐modulating ...
Chanin Sillapachaiyaporn, Wenjing Wang, Yao Qin, Lili Yan, Stephan Scheeff, Xu He, Qiong Wu, Yue Lin, Jinsai Shang, Xin Ye, Jing Liu, Kailei Sun, Chun Wai Yeung, Junzhe Huang, Zhenghui Chen, Xiaodong Liu, Yiqun Geng, Shannon Wing Ngor Au, Bonaventure Y. Ip, Ho Ko, Billy Wai‐Lung Ng   +20 more
wiley   +1 more source

Epidemiology and clinical outcomes of common respiratory viruses detected by multiplex RT-PCR in patients at a national infectious disease reference center in Romania, 2022-2025. [PDF]

Virol J
Vlaicu O, Florea D, Banică L, Paraschiv S, Săndulescu O, Drăgănescu AC, Streinu-Cercel A, Streinu-Cercel A, Oțelea D, Miron VD.   +9 more
europepmc   +1 more source