Results 81 to 90 of about 1,917,084 (305)

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

RT-PCR/Nested conditions for amplification for rotavirus and picobirnavirus.

open access: yes, 2021
RT-PCR/Nested conditions for amplification for rotavirus and picobirnavirus.
Helder Henrique Costa Pinheiro (6095834)   +14 more
core   +1 more source

Low occurrence of Hepatitis A virus in water samples from an urban area of Southern Brazil

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2018
Hepatitis A virus (HAV), a member of Picornaviridae family, is the main causative agent of acute viral hepatitis in the world, mainly in developing countries.
Fernanda Gil de Souza   +4 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Number of positive results obtained by ELISA against DENV, ZIKV, ZEDIII, and NS1 by the ZIKV-RT-PCR-positive, ZIKV-IgM-positive, Flavivirus, and negative groups.

open access: yes, 2019
Number of positive results obtained by ELISA against DENV, ZIKV, ZEDIII, and NS1 by the ZIKV-RT-PCR-positive, ZIKV-IgM-positive, Flavivirus, and negative groups.
Sarah Attoumani (7411418)   +11 more
core   +1 more source

Evaluating an MRNA based body fluid identification test using sybr green fluorescent dye and real-time PCR [PDF]

open access: yes, 2011
The requirement to have more definitive and wider ranging body fluid identification (BFI) tests has resulted in a range of mRNA based real-time PCR BFI assays utilising Taqman fluorescent dye.
Connolly, Jo-Ann, Williams, Graham
core   +3 more sources

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Murine oligonucleotide sequences for q-RT-PCR.

open access: yes, 2018
Murine oligonucleotide sequences for q-RT-PCR.
Madelaine C. Brearley   +15 more
core   +1 more source

Appling real time RT-PCR for bluetongue virus detection in Iran

open access: yesArchives of Razi Institute, 2011
During 2009-10, real time RT-PCR and conventional RT-PCR techniques Used for detecting BTVs RNA in310 blood samples. For real time and gel based RT-PCR segment-1 and segment-10 selected as conservegenes to search any BTV strains. Using these methods, 58 (
Shoshtari, A.   +3 more
doaj  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

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