Results 81 to 90 of about 1,682,968 (306)
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Virology Journal, 2012 Background Human metapneumovirus (hMPV) is a major cause of acute respiratory infections ranging from wheezing to bronchiolitis and pneumonia in children worldwide.
Wang Xiang +7 more
doaj +1 more source
, 2019 Number of positive results obtained by ELISA against DENV, ZIKV, ZEDIII, and NS1 by the ZIKV-RT-PCR-positive, ZIKV-IgM-positive, Flavivirus, and negative groups.
Sarah Attoumani (7411418) +11 more
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Low occurrence of Hepatitis A virus in water samples from an urban area of Southern Brazil
Revista do Instituto de Medicina Tropical de São Paulo, 2018 Hepatitis A virus (HAV), a member of Picornaviridae family, is the main causative agent of acute viral hepatitis in the world, mainly in developing countries.
Fernanda Gil de Souza +4 more
doaj +1 more source
RT-PCR for COVID-19: Diagnosis Made Easy
BioMedica, 2020 Coronavirus disease COVID-19, caused by Severe Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV2), is highly contagious and has been a pandemic since March 2020.
Osheen Sajjad +2 more
doaj +1 more source
RT-PCR primers for CHRN subunits.
, 2018 RT-PCR primers for CHRN subunits.
Shobha Mummalaneni (565983) +6 more
core +1 more source
Cross-validation of spliced junctions using RT-PCR-seq amplification.
, 2022 Cross-validation of spliced junctions using RT-PCR-seq amplification.
Yanxiao Jia (6569447) +8 more
core +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
RT-PCR expression on miRNA and gene.
, 2016 RT-PCR expression on miRNA and gene.
Qingzeng Wang (3154956) +10 more
core +1 more source