Results 61 to 70 of about 1,917,084 (305)

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Incidence of Viral Infection of Main Garlic Growing Areas of Gangwon Province in Korea

open access: yesResearch in Plant Disease, 2013
This research was conducted to investigate the incidence of viral infection in Samcheok-shi and Jeongseongun, main garlic growing areas of Gangwon province in Korea.
Ji-Eun Shin   +2 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

RT-PCR primers used for class I NDVs identification.

open access: yes, 2022
RT-PCR primers used for class I NDVs identification.
Jingjing Wang (140791)   +14 more
core   +1 more source

Occurrence of viruses in Calla and Peruvian lily in Tuscan nurseries and evidence of new viral records in Italy

open access: yesAdvances in Horticultural Science, 2016
In order to evaluate the health status of Calla and Peruvian lily in Tuscan nurseries, 18 viruses belonging to six families and one unassigned virus were assayed. Tests were carried out on 90 Zantedeschia aethiopica plants and 48 Alstroemeria spp. plants
A. Luvisi   +4 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Primers used for real-time RT-PCR

open access: yes, 2016
Primers used for real-time RT ...
Kohta Ohnishi (387891)   +3 more
core   +1 more source

RT-PCR Detection of HIV in Republic of Macedonia

open access: yesBiomolecules & Biomedicine, 2008
The aim of the study was to detect HIV RNA in seropositive patients using RT-PCR method and thus, to establish PCR methodology in the routine laboratory works.
Golubinka Bosevska   +3 more
doaj   +1 more source

Detection and identification of Fabavirus species by one-step RT-PCR and multiplex RT-PCR

open access: yesJournal of Virological Methods, 2014
The genus Fabavirus of the family Secoviridae comprises a group of poorly characterized viruses. To date, only five species have been described: Broad bean wilt virus 1 (BBWV-1), Broad bean wilt virus 2 (BBWV-2), Lamium mild mosaic virus (LMMV), Gentian mosaic virus (GeMV) and Cucurbit mild mosaic virus (CuMMV).
Panno, S   +7 more
openaire   +4 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

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