Results 11 to 20 of about 2,314 (174)
Patient-associated mutations in Drosophila Alk perturb neuronal differentiation and promote survival
Disease Models & Mechanisms, 2022 Activating anaplastic lymphoma kinase (ALK) receptor tyrosine kinase (RTK) mutations occur in pediatric neuroblastoma and are associated with poor prognosis. To study ALK-activating mutations in a genetically controllable system, we employed CRIPSR/Cas9,
Kathrin Pfeifer +7 more
doaj +1 more source
Reports on Geodesy and Geoinformatics, 2021 The problem involving the monitoring of surface ground movements in post-mining areas is particularly important during the period of mine closures. During or after flooding of a mine, mechanical properties of the rock mass may be impaired, and this may ...
Sokoła-Szewioła Violetta +1 more
doaj +1 more source
Geocarto International, 2023 Unmanned aerial vehicles (UAVs) equipped with global navigation satellite system-real-time kinematic (GNSS RTK) receivers allow direct georeferencing of the photogrammetric project without using ground control points (GCPs).
Patricio Martínez-Carricondo +2 more
doaj +1 more source
Pedestrian navigation: how can inertial measurment units assist smartphones?
Российский технологический журнал, 2021 This paper is devoted to construction of reference walking trajectories for developing pedestrian navigation algorithms for smartphones. Such trajectories can be used both for verification of classical algorithms of navigation or for application of ...
I. A. Chistyakov +4 more
doaj +1 more source
Below the Surface: IGF-1R Therapeutic Targeting and Its Endocytic Journey
Cells, 2019 Ligand-activated plasma membrane receptors follow pathways of endocytosis through the endosomal sorting apparatus. Receptors cluster in clathrin-coated pits that bud inwards and enter the cell as clathrin-coated vesicles.
Caitrin Crudden +7 more
doaj +1 more source
Performance analysis of multi-GNSS static and RTK techniques in estimating height differences
International Journal of Digital Earth, 2020 Establishing reliable elevation differences is imperative for most geoscience and engineering applications. This work has traditionally been accomplished through spirit leveling techniques; however, surveyors have been utilizing satellite positioning ...
Ahmed Elaksher +4 more
doaj +1 more source
Static Positioning under Tree Canopy Using Low-Cost GNSS Receivers and Adapted RTKLIB Software
Sensors, 2023 The decrease in costs and dimensions of GNSS receivers has enabled their adoption for a very wide range of users. Formerly mediocre positioning performance is benefiting from recent technology advances, namely the adoption of multi-constellation, multi ...
Julián Tomaštík, Tim Everett
doaj +1 more source
An In-Vehicle Smartphone RTK/DR Positioning Method Combined with OSM Road Network
Remote Sensing, 2023 In vehicle navigation scenarios, the RTK positioning results of smartphones are prone to jumps due to the interference of complex urban environments, and the heading angle of dead reckoning (DR) is prone to divergence.
Fuyou Wang +6 more
doaj +1 more source
Proteogenomic characterization of cholangiocarcinoma
Hepatology, EarlyView., 2022 Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng +18 more
wiley +1 more source
Molecular & Cellular Oncology, 2017 To obtain a global picture of how protein phosphatases are involved in receptor tyrosine kinase (RTK) signaling, we mapped the RTK-phosphatase interactome. Analyses of selected interactions revealed detailed mechanisms of their actions.
Zhong Yao, Igor Stagljar
doaj +1 more source