Results 191 to 200 of about 103,717 (290)

Fibroblasts promote the progression of benign prostatic hyperplasia through colony-stimulating factor 1 receptor-mediated RTK signaling in prostatic epithelial cells. [PDF]

Mol Biomed
Zhan M, Yang R, Gu Y, Zhu J, Guo M, Pupwe G, Huang X, Xu H, Jia Z, Takehiro K, Liu C, Li B, Wang Y, Chen Y, Wang X, Chen Q, Xu B.   +16 more
europepmc   +1 more source

Conformational dynamics in insulin receptor kinase reveal a type III allosteric pocket

Protein Science, Volume 35, Issue 2, February 2026.
Abstract Allosteric modulation is a promising strategy for selective kinase inhibition, yet structural insights into allosteric pockets remain limited across the human kinome. In this work, we present comprehensive characterization of a type III allosteric pocket in the insulin receptor kinase (IRK), integrating structural, conformational, and ...
Jyoti Verma, Harish Vashisth
wiley   +1 more source

Quantifying cancer- and drug-induced changes in Shannon information capacity of RTK signaling. [PDF]

Sci Rep
Nałęcz-Jawecki P, Roth L, Grabowski F, Li S, Kochańczyk M, Bugaj LJ, Lipniacki T.   +6 more
europepmc   +1 more source

Shoreline dynamics of the Danube Delta (2016-2023) measured using GNSS-RTK Technology

Maria Smaranda Ionescu, Adriana Maria Constantinescu, Adrian V. Gheorghe, Alexandru Panin, Albert Scrieciu, Sabin Rotaru, Cristian R. Teodoru, Roberta Castellano, Viorel-Gheorghe Ungureanu, Adrian Stanica   +9 more
openalex   +1 more source

Supplementary Material and Methods from Tumor Intrinsic Efficacy by SHP2 and RTK Inhibitors in KRAS-Mutant Cancers

, 2023
Huai-Xiang Hao, Hongyun Wang, Chen Liu, Steven Kovats, Roberto Velazquez, Hengyu Lu, Bhavesh Pant, Matthew D. Shirley, Matthew J. Meyer, Minying Pu, Joanne Lim, Michael Fleming, LeighAnn Alexander, Ali Farsidjani, Matthew J. LaMarche, Susan E. Moody, Serena J. Silver, Giordano Caponigro, Darrin D. Stuart, Tinya J. Abrams, Peter S. Hammerman, Juliet A. Williams, Jeffrey A. Engelman, Silvia Goldoni, Morvarid Mohseni   +24 more
openalex   +1 more source

Thresholds of Wave Forcing: Implications for Atoll Reef Dynamics Under Sea Level Rise

Journal of Geophysical Research: Oceans, Volume 131, Issue 2, February 2026.
Abstract We investigate the response of shallow reef flow to tidal variability and wave exposure during a 4‐month field campaign in southern Huvadhu Atoll, Maldives. Incident waves breaking on steep fore reefs and reef crests generate a setup proportional to offshore wave height that drives a cross‐reef flow. We emphasize a critical threshold—where the
M. Lindhart, G. Masselink, A. Holsclaw, T. Scott   +3 more
wiley   +1 more source

TAM family kinases are potential candidate targets for therapeutic intervention in chronic myeloid leukemia. [PDF]

Discov Oncol
Yousaf M, Arif K, Khan D.
europepmc   +1 more source

Supplementary Materials and Methods and Supplementary Figures 1 through 7 from Sphingosine Kinase-1 Protects Multiple Myeloma from Apoptosis Driven by Cancer-Specific Inhibition of RTKs

, 2023
Shuntaro Tsukamoto, Yuhui Huang, Motofumi Kumazoe, Connie Lesnick, Shuhei Yamada, Naoki Ueda, Takashi Suzuki, Shuya Yamashita, Yoon Hee Kim, Yoshinori Fujimura, Daisuke Miura, Neil E. Kay, Tait D. Shanafelt, Hirofumi Tachibana   +13 more
openalex   +1 more source

Multispectral Data and LiDAR for Enhanced Georeferencing of Gdanska Glowa's 17th‐Century Fortifications

Archaeometry, Volume 68, Issue 1, Page 94-106, February 2026.
ABSTRACT This study presents a novel remote sensing method to detect 17th‐century environmental elements associated with the historical fortifications of Gdanska Glowa in Poland. By integrating 10‐band multispectral imaging, high‐resolution (1 m) digital elevation models, vegetation metrics and random forest classification within Google Earth Engine ...
Pawel Tysiac, Joanna Dąbal, Tadeusz Widerski   +2 more
wiley   +1 more source

Deciphering the Counterintuitive Role of Vascular Endothelial Growth Factor Signaling Pathways in Pulmonary Arterial Hypertension. [PDF]

Int J Mol Sci
Scagliola R.
europepmc   +1 more source