Results 211 to 220 of about 119,552 (307)

Generation and Dissipation of Infragravity Waves Over Natural and Engineered Chenier Plain During Hurricane Laura

Journal of Geophysical Research: Oceans, Volume 131, Issue 5, May 2026.
Abstract Infragravity (IG) waves play a crucial role in nearshore hydrodynamics and sediment transport; however, their generation and dissipation mechanisms during extreme storms remain challenging to assess due to limited data availability, site‐specific characteristics of natural landscapes, and anthropogenic effects.
Jie Huang, Qin Chen, Ling Zhu, Navid H. Jafari   +3 more
wiley   +1 more source

Direct Selection of Functional De Novo Macrocycles for Activation of On‐Cellulo Insulin Receptor

Angewandte Chemie, Volume 138, Issue 17, 20 April 2026.
A live‐cell screening platform, RaPID‐ExCells, integrates mRNA display‐derived macrocyclic peptide libraries with functional selection against native cell‐surface receptors. Application to the insulin receptor enabled de novo discovery of a macrocyclic agonist that activates endogenous signaling despite weak in vitro binding, highlighting the power of ...
Yun‐Hsuan Kuo, Emiko Mihara, Junichi Takagi, Hiroaki Suga   +3 more
wiley   +2 more sources

The Spatial Signature of Glioblastoma: A Statistical Re-Assessment of Anatomical Distribution Based on Methylation Subtypes. [PDF]

Cells
Herrmann T, Delbridge C, Griessmair M, Canisius J, Mitsdoerffer M, Bernhardt D, Hostettler IC, Negwer C, Yakushev I, Meyer B, Schmidt-Graf F, Combs SE, Kirschke JS, Wiestler B, Metz MC.   +14 more
europepmc   +1 more source

Clinical and Genetic Landscape of Glioblastoma, IDH‐Wildtype With FGFR Gene Family Alterations

Cancer Science, Volume 117, Issue 5, Page 1455-1468, May 2026.
We analyzed 1076 cases of glioblastoma, IDH‐wildtype (GBM, IDH‐wt) using the C‐CAT genomic database to clarify the clinical and genetic features of FGFR alterations. FGFR::TACC fusions and FGFR1 mutations were identified in distinct subsets and were associated with unique co‐mutation patterns.
Yasuhito Kegoya, Yoshihiro Otani, Ryo Mizuta, Ryosuke Ikemachi, Mako Kamiura, Joji Ishida, Shinichi Toyooka, Daisuke Ennishi, Shuta Tomida, Shota Tanaka   +9 more
wiley   +1 more source

Oncologic strategies and options for the management of metastatic thymic carcinoma. [PDF]

Mediastinum
Maniar R, Loehrer PJ.
europepmc   +1 more source

Early‐Onset Digestive System Cancers: Risk Factors and Clinicopathological and Molecular Features Across Organ Sites

Cancer Science, Volume 117, Issue 5, Page 1223-1234, May 2026.
Shared risk factors, clinical features, and tumor characteristics across multiple early‐onset cancer types are shown in this Graphical Abstract. Integrative approaches combining molecular pathology, oncology, and population sciences offer opportunities to clarify underlying mechanisms and help us develop preventive strategies for early‐onset cancers ...
Nobuhiro Nakazawa, Satoko Ugai, Atsushi Kondo, Kosuke Matsuda, Shu Kato, Genki Usui, Shiori Tanaka, Hwa‐Young Lee, Xinyuan Zhang, Hideo Miyagawa, Mai Chan Lau, Hiroshi Saeki, Yukihide Kanemitsu, Andrew T. Chan, Shuji Ogino, Minkyo Song, Juha P. Väyrynen, Tomotaka Ugai   +17 more
wiley   +1 more source

Anion‐Controlled Structural Interconversion of Palladium Cages Enables Separations by Selective Guest Capture and Release

Angewandte Chemie, Volume 138, Issue 16, 13 April 2026.
We report a pair of interconvertible palladium(II) cages assembled from an asymmetric ligand, whose switching is triggered by specific counter‐anions, tetrafluoroborate (BF4−) and bis(trifluoromethanesulfonyl)imide (NTf2−). Their complementary guest preferences enable orthogonal, multi‐cycle catch‐and‐release, exemplified by the selective purification ...
Zhe Li, Tanya K. Ronson, Charlie T. McTernan   +2 more
wiley   +2 more sources

Tislelizumab Combined With Axitinib in Neoadjuvant Treatment of Locally Advanced Clear Cell Renal Cell Carcinoma: A Single-Center, Phase II Clinical Study. [PDF]

MedComm (2020)
Yang W, Zhang S, Liu G, Li H, Wang X, Jiang B, Zhang G, Guo H, Ji C.   +8 more
europepmc   +1 more source

Transcriptional Reinforcement of the HER2–RAS Network in HER2‐Positive Gastric Cancer: The RUNX–SOS1 Axis in Context

Cancer Science, Volume 117, Issue 5, Page 1235-1243, May 2026.
RUNX‐dependent transcriptional control of SOS1 reinforces HER2–RAS signaling and may attenuate responses to HER2‐targeted therapies in HER2‐positive gastric cancer. ABSTRACT HER2‐positive gastric cancer represents a distinct molecular subtype characterized by chromosomal instability, variable HER2 amplification, and substantial intratumoral ...
Tatsuya Masuda, Takayoshi Watanabe, Toshinori Ozaki, Yasuhiko Kamikubo   +3 more
wiley   +1 more source

Loss of <i>CDKN2A/B</i> is a Hallmark of RTK II Glioblastomas. [PDF]

J Cancer
Langwieder CK, Hölzl D, Hutarew G, Schlicker HU, Alinger-Scharinger B, Schwartz C, Sotlar K, Kraus TFJ.   +7 more
europepmc   +1 more source