The role of homeobox genes in signaling pathway positive feedback loops and cancer therapy. [PDF]
Vider BZ.
europepmc +1 more source
Effects of a Catastrophic Debris‐Flow on a Coastal Salt Marsh
Debris‐flows are extreme events that can occur when wildfire is followed by heavy precipitation. Although debris‐flow effects are primarily assessed in montane systems, here, we document the downstream physical and biological impacts of a debris‐flow in a coastal salt marsh.
Rachel S. Smith +6 more
wiley +1 more source
Human brain and organoid transcriptomes reveal key receptor tyrosine kinase pathways and genetic signatures in Alzheimer's disease. [PDF]
Shin S +18 more
europepmc +1 more source
The regulation of stem cell fate and its application in neural regeneration
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He +3 more
wiley +1 more source
Age-Associated NAD+ Decline and Mitochondrial Dysfunction Predispose Cells to a Reversible Tumor-Permissive Metabolic State. [PDF]
Amina B +4 more
europepmc +1 more source
Contactin‐5 (CNTN5) is upregulated in non‐small cell lung cancer (NSCLC) and associated with metastasis and poor prognosis. Mechanistically, CNTN5 interacts with PTPN13 to promote YAP1 nuclear translocation and transcriptional activation, enhancing NSCLC cell migration and invasion in vitro and metastasis in vivo.
Jiarui Wang +6 more
wiley +1 more source
Integrated Mutation Profiling and Prognostic Genomic Signature in Pediatric Testicular and Ovarian Germ Cell Tumors. [PDF]
Xuan X +7 more
europepmc +1 more source
Widespread spring discharge drives major water–salt–heat fluxes in salt marshes
Abstract The occurrence, spatial distribution, and flux significance of submarine groundwater discharge (SGD) through preferential pathways in low‐permeability salt marshes remain poorly understood. Using thermal infrared imaging and in situ measurements, we mapped 983 saline springs in winter and 413 in summer across six tidal creeks on the muddy ...
Lucheng Zhan +4 more
wiley +1 more source
Agricultural machinery operation trajectory identification and operation area estimation for cloud-platform deployment. [PDF]
Li B, Feng Y, Zhou G, Xu P, Wang W.
europepmc +1 more source
Advances in FGF/FGFR Signaling: Implications for Disease and Therapy
The FGF/FGFR signaling is indispensable for the maintenance of physiological homeostasis and governs multiple biological processes, including embryonic development, bone metabolism, angiogenesis, and neurogenesis, whereas aberrant hyperactivation of this pathway drives the progression of malignancies and autoimmune disorders, including inflammatory ...
Miaoyu Song +4 more
wiley +1 more source

