Flavour and Fragrance Journal, Volume 41, Issue 3, Page 696-710, May 2026.We unveil that CLC orchestrates the dual role of eosinophil recruitment via CCL26 and tissue remodelling via POSTN in allergic rhinitis, identifying it as a potential therapeutic target. ABSTRACT Allergic rhinitis (AR) is a chronic airway inflammation driven by a type 2 immune response, yet the molecular mechanisms underlying its persistence and tissue
Fanyu Yuan +9 more
wiley +1 more source
Disrupting the KRAS-SOS1 protein-protein interaction: mechanistic rationale for pan-KRAS pathway suppression and combination therapy. [PDF]
Front ChemKamel EM +7 more
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Comparison of Classic RTK and Network-RTK Methods
Selcuk University Journal of Engineering ,Science and Technology, 2014 Cevat İNAL +2 more
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Targeted Therapy and Immunotherapies in Hepatocellular Carcinoma: Mechanisms and Clinical Studies
MedComm, Volume 7, Issue 5, May 2026.The mechanism of multiple signaling pathways and their related targeted inhibitors in HCC. (A) The mechanism of Ras/Raf/MEK/ERK signaling pathway and its related targeted inhibitors; (B) the mechanism of PI3K/AKT/mTOR signaling pathway and its crosstalk with other pathways and its related targeted inhibitors; (C) the mechanism of JAK/STAT signaling ...
Penghui He +9 more
wiley +1 more source
Targeting CDK11 in Rhabdoid Tumor of the Kidney. [PDF]
Cancers (Basel)Murakami Y +6 more
europepmc +1 more source
Isocitrate Dehydrogenase Mutations in Cancer: From Bench to Bedside Applications
MedComm, Volume 7, Issue 5, May 2026.Mutant isocitrate dehydrogenase affects multiple cancer types. Alterations in IDH1 and IDH2 result in abnormal enzyme activity, leading to the overproduction of D‐2‐hydroxyglutarate (D‐2HG). This metabolite disrupts cellular metabolism and epigenetic regulation, driving cancer initiation, progression, and metastasis.
Yuhan Fang +6 more
wiley +1 more source
Prognostic Impact of RTK-RAS Alterations in FOLFOX-Treated Early-Onset Colorectal Cancer Revealed by Artificial Intelligence-Driven Precision Oncology. [PDF]
Cancers (Basel)Diaz FC +4 more
europepmc +1 more source
Oikos, Volume 2026, Issue 5, May 2026.Habitat‐modifying plants engineer landscapes through plant‐environment feedbacks. The strength of these feedbacks is determined by above‐ and below‐ground traits shaping landscape morphology. Besides interspecific differences, recent findings highlight that intraspecific trait variation, such as shoot density, can also influence landscape morphology ...
Solveig Höfer +9 more
wiley +1 more source
Hidden Markov Models for Bounded, Inflated Time Series: Forecasting Icing on Wind Turbine Blades
Wind Energy, Volume 29, Issue 5, May 2026.ABSTRACT Time series analysis of icing‐induced power loss in wind turbines pose several challenges: the response is bounded, serially dependent, intermittently missing, highly dispersed, and often inflated at a single value. We address these challenges with discrete‐time hidden Markov models for a discrete‐continuous process assumed to follow a mixture
Albert S. Bisgaard +3 more
wiley +1 more source
Evaluation of the Ionospheric Corrections Generated by Smartphones with Different Real-Time Products. [PDF]
Sensors (Basel)Zhang Y, Jiang Y, Gao Y.
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