<i>Aeromonas hydrophila</i> RTX adhesin has three ligand-binding domains that give the bacterium the potential to adhere to and aggregate a wide variety of cell types. [PDF]
Ye Q +10 more
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Microbiological safety and hygiene monitoring of coastal seawater at Northern public beaches of Mauritius and genetic characterization of human pathogenic Vibrio species. [PDF]
Neetoo H +14 more
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Intraarticular resiniferatoxin, a potent TRPV1 agonist, for treatment of osteoarthritic pain. [PDF]
Iadarola MJ +3 more
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LDL receptor-mediated endocytosis of <i>Escherichia coli</i> α-hemolysin mediates renal epithelial toxicity. [PDF]
Kuhn HW +8 more
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CGRP signaling links tumor-associated pain to immune evasion in oral squamous cell carcinoma. [PDF]
McIlvried LA +12 more
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Azathioprine for remission maintenance in anti-interferon-γ autoantibody-associated immunodeficiency syndrome- a retrospective single-center cohort study. [PDF]
Laisuan W +6 more
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Clinical Features and Management of Optic Neuritis in a Cohort of Patients with Combined Central and Peripheral Demyelination. [PDF]
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Bacterial RTX toxins and host immunity
Current Opinion in Infectious Diseases, 2021Purpose of review RTX toxin action often defines the outcome of bacterial infections. Here, we discuss the progress in understanding the impacts of RTX toxin activities on host immunity. Recent findings Bordetella pertussis CyaA activity paralyzes ...
Jawid Nazir, Ahmad, Peter, Sebo
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Interaction of RTX toxins with the host cell plasma membrane
Biological Chemistry, 2023Abstract Repeats in ToXins (RTX) protein family is a group of exoproteins secreted by Type 1 secretion system (T1SS) of several Gram-negative bacteria. The term RTX is derived from the characteristic nonapeptide sequence (GGxGxDxUx) present at the C-terminus of the protein.
Feby M. Chacko, Lutz Schmitt
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The interaction between RTX toxins and target cells
Trends in Microbiology, 1999RTX toxins are important virulence factors produced by a wide range of Gram-negative bacteria. They fall into two categories: the hemolysins, which affect a variety of cell types, and the leukotoxins, which are cell-type- and species-specific. These toxins offer interesting models for targeting, insertion and translocation of aqueous proteins into ...
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