Results 191 to 200 of about 8,609 (220)
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Modification of arginine in sea anemone toxin RTX-III from Radianthus macrodactylus
Toxicon, 1989Chemical modifications of the polypeptide neurotoxin RTX-III have allowed us to study the functional role of Arg residues. The effect of chemical modification has been estimated by measuring toxicity in mice. 2,4-Pentanedione did not react with Arg residues of RTX-III even after 100 hr incubation. Malonic aldehyde reacted readily with RTX-III, yielding
V M, Mahnir +2 more
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Structure and Function of MARTX Toxins and Other Large Repetitive RTX Proteins
Annual Review of Microbiology, 2011The Repeats-in-Toxins (RTX) family of proteins classically consists of cytolysins and hemolysins. Over the past decade, genome sequencing revealed the existence of very large members of this family. These are all repetitive proteins ranging in size from 200 to 900 kDa that function as toxins or adhesins. Many are exported by Type I secretion.
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RTX Toxin Structure and Function: A Story of Numerous Anomalies and Few Analogies in Toxin Biology
2001It can be agreed that RTX toxins contribute to the pathogenesis of different diseases by causing dysfunction of the general cellular reactions of the immune response. The suggestion that RTX toxins induce cytokine production in nonimmune cells that would ultimately cause tissue damage is an expansion of their role in disease pathogenesis (Uhlen et al ...
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The role of RTX toxins in host specificity of animal pathogenic Pasteurellaceae
Veterinary Microbiology, 2011RTX toxins are bacterial pore-forming toxins that are particularly abundant among pathogenic species of Pasteurellaceae, in which they play a major role in virulence. RTX toxins of several primary pathogens of the family of Pasteurellaceae are directly involved in causing necrotic lesions in the target organs.
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Biology and evolution of bacterial toxin–antitoxin systems
Nature Reviews Microbiology, 2022Dukas Jurenas +2 more
exaly
[Interaction between Actinobacillus pleuropneumoniae RTX toxin and host--a review].
Wei sheng wu xue bao = Acta microbiologica Sinica, 2009Actinobacillus pleuropneumoniae (App) is the etiological agent of porcine pleuropneumonia which causes huge economic losses to the pig industry. RTX (repeat in the structural toxin, RTX) is the main virulence-associated factor of the pathogen and, plays a dual role on the pathogen's infection and immunity.
Shengxian, Fan +4 more
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