Genomics of the new species Kingella negevensis: diagnostic issues and identification of a locus encoding a RTX toxin. [PDF]
, 2017 Kingella kingae, producing the cytotoxic RTX protein, is a causative agent of serious infections in humans such as bacteremia, endocarditis and osteoarticular infection, especially in young children.
Greub, G. +7 more
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Molecular characterization of Vibrio cholerae outbreak strains with altered El Tor biotype from southern India [PDF]
, 2009 Forty-four Vibrio cholerae isolates collected over a 7-month period in Chennai, India in 2004 were characterized for gene traits, antimicrobial susceptibility and genomic fingerprints.
A. K. Goel +39 more
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Gangliosides Block Aggregatibacter Actinomycetemcomitans Leukotoxin (LtxA)-Mediated Hemolysis
Toxins, 2010 Aggregatibacter actinomycetemcomitans is an oral pathogen and etiologic agent of localized aggressive periodontitis. The bacterium is also a cardiovascular pathogen causing infective endocarditis. A.
Scott C. Kachlany +5 more
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Membrane localization of the Repeats-in-Toxin (RTX) Leukotoxin (LtxA) produced by Aggregatibacter actinomycetemcomitans. [PDF]
PLoS ONE, 2018 The oral bacterium, Aggregatibacter actinomycetemcomitans, which is associated with localized aggressive periodontitis, as well as systemic infections including endocarditis, produces numerous virulence factors, including a repeats-in-toxin (RTX) protein
Angela C Brown +7 more
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Molecular characterization of an RTX toxin determinant from Actinobacillus suis [PDF]
Infection and Immunity, 1992 RTX cytolysins are a family of calcium-dependent, pore-forming, secreted toxins found in a variety of gram-negative bacteria. The prototypical member of this family is the alpha-hemolysin of Escherichia coli. The RTX genetic determinants from seven members of the family Pasteurellaceae, Pasteurella haemolytica, Actinobacillus actinomycetemcomitans, and
L L, Burrows, R Y, Lo
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mBio, 2019 The Escherichia coli hemolysin (HlyA) is a pore-forming exotoxin associated with severe complications of human urinary tract infections. HlyA is the prototype of the repeats-in-toxin (RTX) family, which includes LtxA from Aggregatibacter ...
Laura C. Ristow +6 more
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Virulence profile comparison between LEE-negative Shiga toxin-producing Escherichia coli (STEC) strains isolated from cattle and humans [PDF]
, 2010 For comparison purposes, the prevalence of 8 virulence markers was investigated, by PCR, in 153 cattle and 47 human Locus for Enterocyte Effacement (LEE)-negative Shiga toxin-producing Escherichia coli (STEC) strains isolated in Argentina.
Galli, Lucía +4 more
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MARTX of Vibrio vulnificus biotype 2 is a virulence and survival factor [PDF]
, 2013 Vibrio vulnificus biotype 2 is a polyphyletic group whose virulence for fish relies on a plasmid. This plasmid contains an rtxA gene duplicated in the small chromosome that encodes a MARTX (Multifunctional, Autoprocessing Repeats-in-Toxin) unique within ...
Amaro +36 more
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Membrane Restructuring by Bordetella pertussis Adenylate Cyclase Toxin, a Member of the RTX Toxin Family [PDF]
Journal of Bacteriology, 2004 ABSTRACT Adenylate cyclase toxin (ACT) is secreted by Bordetella pertussis , the bacterium causing whooping cough. ACT is a member of the RTX (repeats in toxin) family of toxins, and like other members in the family, it may bind cell membranes and cause disruption of the permeability barrier, leading to ...
Martín, César +6 more
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Painful toxins acting at TRPV1 [PDF]
, 2008 Many plant and animal toxins cause aversive behaviors in animals due to their pungent or unpleasant taste or because they cause other unpleasant senstations like pain.
Cromer, B, McIntyre, P
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