Results 11 to 20 of about 2,870 (109)

Differential Induction and Signaling of Type I and III Interferons During Infection of Human Nasal Epithelial Cells With the Four Human Parainfluenza Virus Types. [PDF]

J Med Virol
ABSTRACT Human parainfluenza viruses (HPIVs) commonly cause croup and lower respiratory tract infections in young children. Despite typically self‐limiting with mild symptoms, the innate immune responses to HPIVs remain poorly understood, especially across all four types in human nasal epithelial cells (hNECs), the primary infection site.
Ong HH, Liu J, Thong M, Chow VTK, Su YCF, Smith GJD, Wang DY.   +6 more
europepmc   +2 more sources

Characterization of Exogenous Sequence Fragments in Extracellular Vesicles from Human

Small Structures, Volume 4, Issue 9, September 2023., 2023
Exogenous sequences in human extracellular vesicles (EVs) are identified by sequence alignment. In 1838 EV samples, an average of 21.82% of reads are unmapped to the human genome, and 12.33% are mapped to collected exogenous reference sequences. Parainfluenza virus and mammalian rubulavirus are only identified in lung adenocarcinoma samples and plant ...
Yi Wang, Gui-Yan Xie, Qiong Zhang, Xiuqing Zhang, An-Yuan Guo   +4 more
wiley   +1 more source

Expert opinion on the identification, risk assessment, and mitigation of microorganisms and parasites relevant to xenotransplantation products from pigs

Xenotransplantation, Volume 30, Issue 5, September/October 2023., 2023
Abstract Xenotransplantation has the potential to address shortages of organs available for clinical transplantation, but concerns exist regarding potential risks posed by porcine microorganisms and parasites (MP) to the health of human recipients. In this study, a risk‐based framework was developed, and expert opinion was elicited to evaluate porcine ...
Huybert Groenendaal, Solenne Costard, Reid Ballard, Stephen Bienhoff, Diana C. Challen, Brandon J. Dominguez, Douglas R. Kern, Dan Miller, Jeske Noordergraaf, Larisa Rudenko, Henk‐Jan Schuurman, Tom Spizzo, Matthew Sturos, Bill Zollers, Jay A. Fishman   +14 more
wiley   +1 more source

Epidemiology and clinical manifestations of different enterovirus and rhinovirus types show that EV‐D68 may still have an impact on severity of respiratory infections

Journal of Medical Virology, Volume 94, Issue 8, Page 3829-3839, August 2022., 2022
Abstract Respiratory infections are often caused by enteroviruses (EVs). The aim of this study was to identify whether certain types of EV were more likely to cause severe illness in 2016, when an increasing spread of upper respiratory infections was observed in Gothenburg, Sweden.
Simon B. Larsson, Diana Vracar, Marie Karlsson, Johan Ringlander, Heléne Norder   +4 more
wiley   +1 more source

Zoonotic and reverse zoonotic transmission of viruses between humans and pigs

APMIS, Volume 129, Issue 12, Page 675-693, December 2021., 2021
Humans and pigs share a close contact relationship, similar biological traits, and one of the highest estimated number of viruses compared to other mammalian species. The contribution and directionality of viral exchange between humans and pigs remain unclear for some of these viruses, but their transmission routes are important to characterize in ...
Helena Aagaard Glud, Sophie George, Kerstin Skovgaard, Lars Erik Larsen   +3 more
wiley   +1 more source

‘Keeping the kids at home’ can limit the persistence of contagious pathogens in social animals

Journal of Animal Ecology, Volume 90, Issue 11, Page 2523-2535, November 2021., 2021
Using a spatially implicit individual‐based susceptible‐infected‐recovered (SIR) model, the authors show that in host populations where juveniles are isolated from contact with individuals in other social groups, the transmission and persistence of contagious pathogens is reduced.
Lucile Marescot, Mathias Franz, Sarah Benhaiem, Heribert Hofer, Cédric Scherer, Marion L. East, Stephanie Kramer‐Schadt   +6 more
wiley   +1 more source

First report of porcine parainfluenza virus 1 (species Porcine respirovirus 1) in Europe

Transboundary and Emerging Diseases, Volume 68, Issue 4, Page 1731-1735, July 2021., 2021
Abstract Porcine respirovirus 1, also known as Porcine parainfluenza virus 1 (PPIV‐1) was first identified in Hong Kong in 2013, later in the USA and most recently in Chile. Here, we report the first detection of PPIV‐1 outside these three regions. We screened 22 farms in Hungary by testing 15 nasal swab samples obtained from 3‐week‐old piglets (3 ...
Lilla Dénes, Attila Cságola, Kitti Schönhardt, Máté Halas, Norbert Solymosi, Gyula Balka   +5 more
wiley   +1 more source

Clinical and Epidemiological Insights into a Parainfluenza Virus Type 3 Outbreak in Multiple Myeloma Patients. [PDF]

J Med Virol
ABSTRACT Human parainfluenza virus type 3 (HPIV‐3) can be responsible for mild to severe respiratory infections and hospital epidemics. We investigated an outbreak in a hematology unit. Respiratory viruses were screened using multiplex PCR. HPIV‐3 quantification and whole‐genome sequencing were performed on HPIV‐3 positive respiratory samples. Clinical
Timsit S, Mellon G, Forgeard N, Mercier-Delarue S, Mahjoub N, Euzen V, Harel S, Elessa D, Osinski N, Diaz E, Royer B, Arnulf B, Salmona M, Legoff J.   +13 more
europepmc   +2 more sources

From conifers to cognition: Microbes, brain and behavior

Genes, Brain and Behavior, Volume 19, Issue 8, November 2020., 2020
A century ago biologists were surprised to discover live microbes (endophytes) within healthy plant tissues. It is now apparent that this is also true of mammals where, in addition to the gut microbiome, a diversity of endogenous microbes (endozoites) are present in multiple tissues including the brain.
Richard Lathe, David St. Clair
wiley   +1 more source

Deep Parotid Lobe Abscess Presenting with Dysphagia and Trismus

Case Reports in Otolaryngology, Volume 2019, Issue 1, 2019., 2019
An abscess of the deep parotid lobe is an uncommon complication of acute parotitis. Characterized by warm erythematous facial skin and ipsilateral cheek swelling, parotid abscesses have often been associated with decreased saliva production and immunodeficiency.
Madison Grinnell, Andrew Logeman, Timothy Knudsen, Zafar Sayed, Kamal Morshed   +4 more
wiley   +1 more source