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A reply to behavior analysts writing about rules and rule-governed behavior [PDF]

The Analysis of Verbal Behavior, 1990
Verbal stimuli called "rules" or "instructions" continue to be interpreted as discriminative stimuli despite recent arguments against this practice. Instead, it might more fruitful for behavior analysts to focus on "contingency-specifying stimuli" which are function-altering. Moreover, rather than having a special term, "rule," for verbal stimuli whose
openaire   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

An analysis of the effects of history of behavioral variation on rule-following behavior / Análise dos efeitos de histórias de variação comportamental sobre o seguimento de regras

Psicologia: Reflexão e Crítica, 2004
In a study concerning the sensitivity of instruction-following to signaled changes in contingencies, 14 children in the 8-to-9 age range were exposed to a matching-to-sample procedure.
José Guilherme Wady Santos, Carla Cristina Paiva Paracampo, Luiz Carlos de Albuquerque   +2 more
doaj  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Analyzing the role of social variables and programmed consequences in instruction-following / Análise do papel de variáveis sociais e de conseqüências programadas no seguimento de instruções

Psicologia: Reflexão e Crítica, 2004
Twelve children in the eight-to-nine year age range were exposed to a matching-to-sample procedure in an investigation dealing with the role of monitoring in instruction-following.
Niele Márcia Amaral de Albuquerque, Carla Cristina Paiva Paracampo, Luiz Carlos de Albuquerque   +2 more
doaj  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

RESOLUÇÃO DE PROBLEMAS NA ATENÇÃO AMBULATORIAL DA ESQUIZOFRENIA

Psicologia, 2005
After the psychiatric reformation many families of users of mental health services come to face problems related to ambulatorial settings of treatment.
Mário Gomes de Figueirêdo, Elizeu Batista Borloti   +1 more
doaj  

Is Arabic punctuation rule-governed?

Cogent Arts & Humanities
This paper investigates the extent to which Arabic punctuation is rule-governed, with the aim of improving text comprehension, disambiguation, and machine translation.
Sane Yagi, Shehdeh Fareh, Ashraf Elnagar, Mariam Balajeed, Abdalla El-mneizel, Mohammad Al-Badawi   +5 more
doaj   +1 more source