Results 91 to 100 of about 2,026 (216)

Flow-Induced Fatigue Damage of Large Francis Turbines Under Multiple Operating Loads

Applied Sciences
The Francis runner is a critical component of the Francis turbine generator unit, playing a central role in converting water energy into rotating mechanical energy that drives the generator in hydropower stations.
Pinghu Liu, Xingxing Huang, Tianyu Yang, Zhengwei Wang   +3 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Numerical parametric study of a Kaplan turbine incorporated with a sub runner considering analysis of hydraulic dissipation

Results in Engineering
In this paper, a novel approach on Kaplan turbines, proposed and published in a US patent, has been investigated numerically using CFD tool. This approach includes the incorporation of an extra runner, called sub runner, into the main runner of a typical
Amirhossein Khoddami, Mojtaba Tahani, Fathollah Pourfayaz, Alireza Riasi, Khalil Allah Sajadian   +4 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Solid–Liquid Flow Analysis of Francis‐99 Turbine Runner: Effects of Sediment Concentration

Energy Science & Engineering
This study examines the behavior of solid–liquid two‐phase flow within the runner of the Francis‐99 turbine. Numerical simulations were carried out by Ansys Fluent software using the Mixture multiphase flow model along with the Realizable k‐ε turbulence ...
Kang Xu, Pinyu Xiang, Ziyao Zhou, Yufan Xiong, Zhishun Yu, Xiaobing Liu, Jiayang Pang   +6 more
doaj   +1 more source

Reducing red light proportion in full-spectrum LEDs enhances runner plant propagation by promoting the growth and development of mother plants in strawberry

Frontiers in Plant Science
Full-spectrum light-emitting diodes (LEDs) have gradually replaced narrow-spectrum LEDs and are widely used in plant factories with artificial lighting (PFALs).
Jian Chen, Fang Ji, Rongwei Gao, Dongxian He   +3 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source