Results 81 to 90 of about 59,033 (250)

Billy Heavy Runner interview

open access: yes, 1973
7 p. transcript of an interview with Useless Good Runner (Billy Heavy Runner), conducted by Dila Provost and Albert Yellowhorn on an unknown date, probably between 1970 and 1975. Tape number IH-AA.234, transcript disc 2.Discusses Treaty 7: events leading
Yellowhorn, Albert   +2 more
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Reference Values for Hydration Biomarkers: Optimizing Athletic Performance and Recovery

open access: yesOpen Access Journal of Sports Medicine
Lawrence E Armstrong,1 Rebecca L Stearns,1 Robert A Huggins,1 Yasuki Sekiguchi,2 April J Mershon,3 Douglas J Casa1 1Department of Kinesiology, Korey Stringer Institute, University of Connecticut, Storrs, CT, 06269-1110, USA; 2Department of Kinesiology ...
Armstrong LE   +5 more
doaj  

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Thomasjkeel/jsmetrics-analysis-runner: 1.0.0

open access: yes
<p>Initial release</p> <p><strong>Full Changelog</strong>: https://github.com/Thomasjkeel/jsmetrics-analysis-runner/compare/v1.0.0...1.0.0</p ...
Tom Keel
core   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

Thomasjkeel/jsmetrics-analysis-runner: v1.0.0

open access: yes
<p>Initial release for zenodo</p> <p><strong>Full Changelog</strong>: https://github.com/Thomasjkeel/jsmetrics-analysis-runner/commits/v1.0.0</p ...
Tom Keel
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Strawberry Plant Propagation: Evaluation of Cultivars Using Different Growing Environments and Assessment Approaches

open access: yesHortScience
Strawberry branch crown development is often associated with yield and berry size. The propagation rate of strawberry cultivars is key to their establishment and longevity in the industry.
Kim S. Lewers, Bryan T. Vinyard
doaj   +1 more source

Dynamic equation and response of turbine runner blade under flow excitation

open access: yesAdvances in Mechanical Engineering, 2018
Considering the complex vibration phenomenon of turbine runner blades under the flow excitation, the nonlinear coupling dynamic equation, which contains hydraulic parameters and blade structure parameters, is established by the finite element method ...
Zhaojun Li   +4 more
doaj   +1 more source

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