Results 241 to 250 of about 8,739 (269)

Deleterious phenotypes in wild Arabidopsis arenosa populations are common and linked to runs of homozygosity. [PDF]

open access: yesG3 (Bethesda)
Barragan AC   +9 more
europepmc   +1 more source

Joint Estimates of Heterozygosity and Runs of Homozygosity for Modern and Ancient Samples [PDF]

open access: yesGenetics, 2019
Abstract Both the total amount and the distribution of heterozygous sites within individual genomes are informative about the genetic diversity of the population they belong to. Detecting true heterozygous sites in ancient genomes is complicated by the generally limited coverage achieved and the presence of post-mortem damage inflating ...
Gabriel Renaud   +2 more
exaly   +9 more sources

A Comprehensive Analysis of Runs of Homozygosity of Eleven Cattle Breeds Representing Different Production Types [PDF]

open access: yesAnimals, 2019
In the presented research, BovineSNP50 microarrays (Illumina) were applied to determine runs of homozygosity in the genomes of 11 cattle breeds maintained in Poland.
Tomasz Szmatoła   +2 more
exaly   +2 more sources

No evidence for excess runs of homozygosity in bipolar disorder

Psychiatric Genetics, 2009
Recent studies have reported large common regions of homozygosity (ROHs) that are the result of autozygosity, that is, the cooccurrence within individuals of long haplotypes that have a high frequency in the population. A recent study reports that such regions are found more commonly in individuals with schizophrenia compared with controls, and ...
Anna E, Vine   +10 more
openaire   +2 more sources

Runs of homozygosity: current knowledge and applications in livestock

Animal Genetics, 2016
SummaryThis review presents a broader approach to the implementation and study of runs of homozygosity (ROH) in animal populations, focusing on identifying and characterizing ROH and their practical implications. ROH are continuous homozygous segments that are common in individuals and populations.
E, Peripolli   +5 more
openaire   +2 more sources

Properties of Runs of Homozygosity as a Measure of Identity by Descent

Journal of Animal Breeding and Genetics
ABSTRACT Runs of Homozygosity (ROH) are commonly used to quantify autozygosity/identity‐by‐descent (IBD) in an individual or population. However, the method's accuracy at the segment level in livestock populations has only been evaluated in a few studies. Thus, the aim of this study was to determine to what extent
Oda B. Wæge   +3 more
openaire   +2 more sources

Whole-genome SNP markers reveal runs of homozygosity in indigenous cattle breeds of Pakistan

Animal Biotechnology, 2023
Muhammad Saif-Ur-Rehman   +2 more
exaly  

Runs of homozygosity and levels of inbreeding in cattle breeds.

2011
Inbreeding results in identity by descent of maternally and paternally inherited alleles. Due to the process of recombination that combines maternal and paternal DNA in very large chunks during meiosis, inbreeding to a recent ancestor results in relatively long homozygous segments of the genome, "runs of homozygosity".
Ferencakovic, M   +7 more
openaire   +2 more sources

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